ArticleJournal of clinical microbiology2012
Detection of negative-sense RNA in packaged hepatitis E virions by use of an improved strand-specific reverse transcription-PCR method.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Non-parasite genome encoded virus-like RNAs reprogram the pathogenicity of human blood flukes.Nature communications · 2025Article
- Detection methods targeting the positive- and negative-sense RNA transcripts from plus-stranded RNA viruses.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022Article
- Hepatitis E Virus Persistence and/or Replication in the Peripheral Blood Mononuclear Cells of Acute HEV-Infected Patients.Frontiers in microbiology · 2021Article
- A strand-specific real-time quantitative RT-PCR assay for distinguishing the genomic and antigenomic RNAs of Rift Valley fever phlebovirus.Journal of virological methods · 2019Article
- Novel Synthesis and Phenotypic Analysis of Mutant Clouds for Hepatitis E Virus Genotype 1.Journal of virology · 2018Article
- Application of Various Types of Liposomes in Drug Delivery Systems.Advanced pharmaceutical bulletin · 2017Article
- Expansion of antisense lncRNA transcriptomes in budding yeast species since the loss of RNAi.Nature structural & molecular biology · 2016Article
- Article
- Analysis of helicase domain mutations in the hepatitis E virus derived from patients with fulminant hepatic failure: effects on enzymatic activities and virus replication.Virus research · 2014Article
- Analysis of antiviral response in human epithelial cells infected with hepatitis E virus.PloS one · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current hepatitis E virus (HEV) negative-sense RNA detection assays have the drawback of false positivity. cDNA synthesis using tag-based primer and Superscript RT-III followed by exonuclease I treatment increased the specificity. Assays could detect as few as 10 copies of negative-sense RNA and could be used in detecting low levels of HEV replication in cells. Virus particles in stool samples of hepatitis E patients showed encapsidation of negative-sense RNA along with HEV genomic RNA.
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