ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2012
β4 integrin marks interstitial myogenic progenitor cells in adult murine skeletal muscle.
Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function.Skeletal muscle · 2020Article
- Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis.Cell death and differentiation · 2020Article
- The effect of type 2 diabetes mellitus and obesity on muscle progenitor cell function.Stem cell research & therapy · 2019Review
- High-resolution myogenic lineage mapping by single-cell mass cytometry.Nature cell biology · 2017Article
- Meta-fibrosis links positive energy balance and mitochondrial metabolism to insulin resistance.F1000Research · 2017Review
- Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.Circulation research · 2016Review
- Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signalling.Nature communications · 2014Article
- Transforming growth factor-beta (TGF- β) signaling in paravertebral muscles in juvenile and adolescent idiopathic scoliosis.BioMed research international · 2014Article
- Cellular dynamics in the muscle satellite cell niche.EMBO reports · 2013Review
- Sources for skeletal muscle repair: from satellite cells to reprogramming.Journal of cachexia, sarcopenia and muscle · 2013Article
- Intrinsic ability of adult stem cell in skeletal muscle: an effective and replenishable resource to the establishment of pluripotent stem cells.Stem cells international · 2013Article
- Article
- Sca-1 is involved in the adhesion of myosphere cells to αVβ3 integrin.Biology open · 2012Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
Skeletal muscle growth and its regeneration following injury rely on myogenic progenitor cells, a heterogeneous population that includes the satellite cells and other interstitial progenitors. The present study demonstrates that surface expression of β4 integrin marks a population of vessel-associated interstitial muscle progenitor cells. Muscle β4 integrin-positive cells do not express myogenic markers upon isolation. However, they are capable of undergoing myogenic specification in vitro and in vivo: β4 integrin cells differentiate into multinucleated myotubes in culture dishes and contribute to muscle regeneration upon delivery into diseased mice. Subfractionation of β4 integrin-expressing cells based on CD31 expression does not further enrich for myogenic precursors. These findings support the expression of β4 integrin in interstitial, vessel-associated cells with myogenic activity within adult skeletal muscle.
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Registered trials
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