Evidence map›Paper›PMID 22205548›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2012

Swallowing dysfunction in cancer patients.

Dysphagia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO), Judith E Raber-Durlacher, Mike T Brennan, Irma M Verdonck-de Leeuw, Rachel J Gibson, June G Eilers, Tuomas Waltimo, Casper P Bots, Marisol Michelet, Thomas P Sollecito and 6 more

Open access · hybridAbstract readReview
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 11 pooled it
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 11 syntheses or guidelines pooled it, 186 citations in OpenAlex.

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  5. The effect of hyperbaric oxygen therapy in head and neck cancer patients with radiation induced dysphagia-a systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
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  10. The life experience of nutrition impact symptoms during treatment for head and neck cancer patients: a systematic review and meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 5 countries.

Dysphagia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO)
Judith E Raber-Durlacher
Mike T Brennan
Irma M Verdonck-de Leeuw
Rachel J Gibson
June G Eilers
Tuomas Waltimo
Casper P Bots
Marisol Michelet
Thomas P Sollecito
Tanya S Rouleau
Aniel Sewnaik
Rene-Jean Bensadoun
Monica C Fliedner
Sol Silverman
Fred K L Spijkervet
Academic Center for Dentistry Amsterdam · NLCarolinas Medical Center · USAmsterdam UMC Location VUmc · NLErasmus MC · NLUniversité de Poitiers · FRUniversity Hospital of Bern · CHUniversity Medical Center Groningen · NLUniversity of Adelaide · AUUniversity of Basel · CHUniversity of California, San Francisco · USUniversity of Nebraska Medical Center · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDysphagia (swallowing dysfunction) is a debilitating, depressing, and potentially life-threatening complication in cancer patients that is likely underreported. The present paper is aimed to review relevant dysphagia literature between 1990 and 2010 with a focus on assessment tools, prevalence, complications, and impact on quality of life in patients with a variety of different cancers, particularly in those treated with curative chemoradiation for head and neck cancer.

methodsThe literature search was limited to the English language and included both MEDLINE/PubMed and EMBASE. The search focused on papers reporting dysphagia as a side effect of cancer and cancer therapy. We identified relevant literature through the primary literature search and by articles identified in references.

resultsA wide range of assessment tools for dysphagia was identified. Dysphagia is related to a number of factors such as direct impact of the tumor, cancer resection, chemotherapy, and radiotherapy and to newer therapies such as epidermal growth factor receptor inhibitors. Concomitant oral complications such as xerostomia may exacerbate subjective dysphagia. Most literature focuses on head and neck cancer, but dysphagia is also common in other types of cancer.

conclusionsSwallowing impairment is a clinically relevant acute and long-term complication in patients with a wide variety of cancers. More prospective studies on the course of dysphagia and impact on quality of life from baseline to long-term follow-up after various treatment modalities, including targeted therapies, are needed.

Indexed as

Antineoplastic AgentsCausalityChemoradiotherapyComorbidityDeglutition DisordersErbB ReceptorsHead and Neck NeoplasmsHumansNeoplasmsPostoperative ComplicationsPrevalenceQuality of LifeXerostomiaAntineoplastic AgentsErbB Receptors

Identifiers

PMID22205548
PMCPMC3271214
OpenAlexW2067059691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.