Evidence map›Paper›PMID 22205518›Full record

ReviewNature methods2011

Power tools for gene expression and clonal analysis in Drosophila.

Alberto del Valle Rodríguez, Dominic Didiano, Claude Desplan

Abstract readReview
In one paragraph

Review in Nature methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Why just fly?Fly · 2025
    Review
  8. Article
  9. Article
  10. Microbes and diet reshape the intestine via distinct cellular dynamics.bioRxiv : the preprint server for biology · 2025
    Article
  11. eNeuro · 2025
    Article
  12. Searching for partners.Science (New York, N.Y.) · 2025
    Article
  13. Article
  14. Article
  15. The Power of Drosophila in Modeling Cancer Cachexia.Advances in experimental medicine and biology · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alberto del Valle RodríguezDepartment of Biology, New York University, New York, New York, USA.
Dominic Didiano
Claude Desplan

Funding

Signaling from photoreceptors to the optic lobesR01EY013012 · NEI · NEW YORK UNIVERSITY · PI DESPLAN, CLAUDE · 1999 to 2024
$9.4M
Defining the Transcription Factor code for medulla neurons.F32EY021065 · NEI · NEW YORK UNIVERSITY · PI DIDIANO, DOMINIC M · 2010 to 2013
$154k
NEI NIH HHS 1F32EY021065NEI NIH HHS EY13012NEI NIH HHS F32 EY021065NEI NIH HHS R01 EY013012
6 · The paper itself

Abstract

The development of two-component expression systems in Drosophila melanogaster, one of the most powerful genetic models, has allowed the precise manipulation of gene function in specific cell populations. These expression systems, in combination with site-specific recombination approaches, have also led to the development of new methods for clonal lineage analysis. We present a hands-on user guide to the techniques and approaches that have greatly increased resolution of genetic analysis in the fly, with a special focus on their application for lineage analysis. Our intention is to provide guidance and suggestions regarding which genetic tools are most suitable for addressing different developmental questions.

Indexed as

Gene ExpressionAnimalsBacterial ProteinsCell LineageClonal EvolutionClone CellsDrosophila melanogasterDrosophila ProteinsGenetic TechniquesLexA Repressor ProteinSerine EndopeptidasesTranscription FactorsTransgenesBacterial ProteinsDrosophila ProteinsGAL4 protein, DrosophilaLexA Repressor ProteinSerine EndopeptidasesTranscription Factors

Identifiers

PMID22205518
PMCPMC3574576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.