Evidence map›Paper›PMID 22205305›Full record

ArticleThe Journal of investigative dermatology2012

Physical and mental impact of psoriasis severity as measured by the compact Short Form-12 Health Survey (SF-12) quality of life tool.

Ivan Grozdev, Douglas Kast, Lauren Cao, Diana Carlson, Prasad Pujari, Brian Schmotzer, Denise Babineau, Elizabeth Kern, Thomas McCormick, Kevin D Cooper and 1 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of investigative dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Topical Diacerein Decreases Skin and Splenic CD11cInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
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  15. Article
  16. Health-related quality of life in morphoea.The British journal of dermatology · 2015
    Article
  17. Article
  18. Article
  19. Quality of life in psoriatic patients: a study using the short form-36.International journal of preventive medicine · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ivan GrozdevDepartment of Dermatology, Murdough Family Center for Psoriasis, University Hospitals Case Medical Center, Case Western Reserve University Cleveland, Cleveland, Ohio 44106, USA.
Douglas Kast
Lauren Cao
Diana Carlson
Prasad Pujari
Brian Schmotzer
Denise Babineau
Elizabeth Kern
Thomas McCormick
Kevin D Cooper
Neil J Korman
University Hospitals Cleveland Medical Center · USUniversity Hospitals of Cleveland · US

Funding

Vitamin D endocrine system and Protection Against Skin TumorlgenesisP30AR039750 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1988 to 2015
$9.1M
Systems Biology CoreP50AR055508 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI BARON, ELMA D · 2007 to 2011
$6.8M
Psoriatic Regulatory T cell DysfunctionR01AR051498 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 2004 to 2014
$3.5M
NIAMS NIH HHS P30 AR039750NIAMS NIH HHS P50 AR055508NIAMS NIH HHS R01 AR051498
6 · The paper itself

Abstract

The Short Form-12 Health Survey (SF-12) is used to assess the patient's quality of life (QoL) using the physical component score (PCS) and the mental component score (MCS). The purpose of this study was to determine whether the SF-12 PCS and MCS are associated with psoriasis severity and to compare QoL between Murdough Family Center for Psoriasis (MFCP) patients and patients with other major chronic diseases included in the National Survey of Functional Health Status data. We used data from 429 adult patients enrolled in MFCP. Psoriasis Area Severity Index (PASI) was used to assess psoriasis severity at the time of completion of the SF-12 questionnaire. Other variables included age, sex, body mass index, psoriatic arthritis, psychiatric disorders, and comorbidities. Linear regression models were used to estimate effect sizes ± 95% confidence intervals. For every 10-point increase in PASI, there was a 1.1 ± 1.3 unit decrease in MCS (P=0.100) and a 2.4 ± 1.3 unit decrease in PCS (P<0.001). Psoriasis severity was associated with PCS and MCS after adjusting for variables, although the strength of the relationship was attenuated in some models. Psoriasis severity is associated with decreased QoL. SF-12 may be a useful tool for assessing QoL among psoriasis patients.

Indexed as

Health SurveysQuality of LifeSeverity of Illness IndexAdultComorbidityFemaleHumansLinear ModelsMaleMental DisordersMiddle AgedPsoriasisReproducibility of ResultsSurveys and QuestionnairesUnited States

Identifiers

PMID22205305
PMCPMC3366426
OpenAlexW1990074846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.