ArticleMolecular biotechnology2012
Isolation, characterization, and structure analysis of a non-TIR-NBS-LRR encoding candidate gene from MYMIV-resistant Vigna mungo.
Article in Molecular biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 61 citations in OpenAlex.
- Durable Management of Plant Viruses: Insights into Host Resistance and Tolerance Mechanisms.Biology · 2026Review
- Allelic differences within DNA polymerase delta subunit 1 correlate with geminivirus resistance in diverse plants.G3 (Bethesda, Md.) · 2025Article
- Genome-wide association mapping of biochemical traits and its correlation with MYMIV resistance in mungbean (Vigna radiata L. Wilczek).Scientific reports · 2024Article
- Salicylic Acid-Induced Expression Profiles of LRR and LRR-RLK Candidate Genes ModulatePlants (Basel, Switzerland) · 2024Article
- Article
- Genome-wide association studies for earliness, MYMIV resistance, and other associated traits in mungbean (PeerJ · 2024Article
- The Hypersensitive Response to Plant Viruses.Viruses · 2023Review
- Farmyard manure, a potential organic additive to reclaim copper and Macrophomina phaseolina stress responses in mash bean plants.Scientific reports · 2023Article
- Review
- A source of resistance against yellow mosaic disease in soybeans correlates with a novel mutation in a resistance gene.Frontiers in plant science · 2023Article
- Tsw - A case study on structure-function puzzles in plant NLRs with unusually large LRR domains.Frontiers in plant science · 2022Article
- Engineering Resistance Against Viruses in Field Crops Using CRISPR- Cas9.Current genomics · 2021Review
- Resistance induction based on the understanding of molecular interactions between plant viruses and host plants.Virology journal · 2021Review
- Review
- The NLR Protein Encoded by the Resistance GeneFrontiers in plant science · 2020Article
- Yellow Mosaic Disease (YMD) of Mungbean (Frontiers in plant science · 2020Review
- Host factors against plant viruses.Molecular plant pathology · 2019Review
- Complex molecular mechanisms underlying MYMIV-resistance in Vigna mungo revealed by comparative transcriptome profiling.Scientific reports · 2019Article
- An NB-LRR gene, TYNBS1, is responsible for resistance mediated by the Ty-2 Begomovirus resistance locus of tomato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Genome-scale examination of NBS-encoding genes in blueberry.Scientific reports · 2018Article
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yellow mosaic disease of Vigna mungo caused by Mungbean yellow mosaic India virus (MYMIV) is still a major threat in the crop production. A candidate disease resistance (R) gene, CYR1 that co-segregates with MYMIV-resistant populations of V. mungo has been isolated. CYR1 coded in silico translated protein sequence comprised of 1,176 amino acids with coiled coil structure at the N-terminus, central nucleotide binding site (NBS) and C-terminal leucine-rich repeats (LRR) that belongs to non-TIR-NBS-LRR subfamily of plant R genes. CYR1 transcript was unambiguously expressed during incompatible plant virus interactions. A putative promoter-like sequence present upstream of this candidate gene perhaps regulates its expression. Enhanced transcript level upon MYMIV infection suggests involvement of this candidate gene in conferring resistance against the virus. In silico constructed 3D models of NBS and LRR regions of this candidate protein and MYMIV-coat protein (CP) revealed that CYR1-LRR forms an active pocket and successively interacts with MYMIV-CP during docking, like that of receptor-ligand interaction; indicating a critical role of CYR1 as signalling molecule to protect V. mungo plants from MYMIV. This suggests involvement of CYR1 in recognizing MYMIV-effector molecule thus contributing to incompatible interaction. This study is the first stride to understand molecular mechanism of MYMIV resistance.
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