ArticleCardiovascular diabetology2011
The association between glucometabolic disturbances, traditional cardiovascular risk factors and self-rated health by age and gender: a cross-sectional analysis within the Malmö Preventive Project.
Article in Cardiovascular diabetology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 27 citations in OpenAlex.
- Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences.Journal of thrombosis and thrombolysis · 2026Article
- Procalcitonin as a Predictive Marker of Incident Liver Disease.Liver international : official journal of the International Association for the Study of the Liver · 2025Article
- Association between changed self-rated health and the risk of venous thromboembolism in Malmö Preventive Program: a cohort study.Journal of thrombosis and thrombolysis · 2024Article
- Uncontrolled blood pressure among hypertensive adults with rheumatoid arthritis in Saudi Arabia: A cross-sectional study.Medicine · 2022Observational
- Copeptin as a predictive marker of incident heart failure.ESC heart failure · 2021Article
- The joint association of self-rated health and diabetes status on 14-year mortality in elderly men and women.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Serum cystatin C and neutrophil gelatinase-associated lipocalin in predicting the severity of coronary artery disease in diabetic patients.Anatolian journal of cardiology · 2016Article
- Cardiovascular risk stratification and management in pre-diabetes.Current diabetes reports · 2014 · on this mapReview
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- Heterogeneous behavior of lipids according to HbA1c levels undermines the plausibility of metabolic syndrome in type 1 diabetes: data from a nationwide multicenter survey.Cardiovascular diabetology · 2012Article
- Both cardiovascular and non-cardiovascular comorbidity are related to health status in well-controlled type 2 diabetes patients: a cross-sectional analysis.Cardiovascular diabetology · 2012Article
- Personal attributes that influence the adequate management of hypertension and dyslipidemia in patients with type 2 diabetes. Results from the DIAB-CORE Cooperation.Cardiovascular diabetology · 2012Article
- Cystatin C and asymptomatic coronary artery disease in patients with metabolic syndrome and normal glomerular filtration rate.Cardiovascular diabetology · 2012Article
- Sex-specific outcomes of diabetic patients with acute myocardial infarction who have undergone percutaneous coronary intervention: a register linkage study.Cardiovascular diabetology · 2012Article
- Gender disparities in diabetes and coronary heart disease medication among patients with type 2 diabetes: results from the DIANA study.Cardiovascular diabetology · 2012Article
- Shadow of diabetes over cardiovascular disease: comparative quantification of population-attributable all-cause and cardiovascular mortality.Cardiovascular diabetology · 2012Article
- Determinants of uncontrolled hypertension in adult type 2 diabetes mellitus: an analysis of the Malaysian diabetes registry 2009.Cardiovascular diabetology · 2012Article
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4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe increased risk of cardiovascular disease (CVD) in diabetic compared to non-diabetic subjects seems to decrease with age. Whether this age-related reduction applies to CVD risk factors, and whether it is limited to established diabetes mellitus (DM) or also applies to pre-diabetic conditions are not well known.
methodsUsing a cross-sectional design we compared the strength of the correlation between glucometabolic disturbances (by grouping), CVD risk factor burden and self-rated health, in two age groups: middle-aged (57-69 years) and older (70-86 years) subjects, (63% men), participating in the Malmö Preventive Project Re-examination Study (n=18,238). Simple (unadjusted) logistic regression analysis was applied to estimate between-group differences and trends. Interaction analysis was applied to estimate differences between age groups.
resultsCVD risk factor burden and the proportion of subjects reporting poor self-rated health increased with increasing glucometabolic disturbance for men and women in both age groups (p-trend<0.0001 for all). The slope of the trend curve with increasing CVD risk factor burden was significantly steeper for older women than for older men (p-interaction=0.002). The slope of the trend curve for poor self-rated health was significantly steeper for middle-aged than for older men (p-interaction=0.005), while no difference was observed between the age groups among women (p-interaction=0.97).
conclusionsWe found no reduction in risk factor accumulation with increasing glucometabolic disturbance between middle-aged and older subjects. Our results indicate life-long CVD risk factor clustering with increased glucometabolic disturbance, and suggest that previously observed age-related reduction in excess CVD risk for subjects with DM might be due to a survival bias. However, our observations indicate more pronounced risk factor clustering and worse self-rated health with increased glucometabolic disturbance in older women than in older men.
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