Evidence map›Paper›PMID 22204421›Full record

ReviewGenome biology2011

Alu elements: know the SINEs.

Prescott Deininger

Abstract readReview
In one paragraph

Review in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 407 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
407citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

407 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Machine learning reveals sequence and genomic context features underlyingbioRxiv : the preprint server for biology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Pathogenic mobile element insertion in theJournal of medical genetics · 2026
    Article
  12. Article
  13. Article
  14. mNature communications · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

347 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Prescott DeiningerTulane Cancer Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA. pdeinin@tulane.edu

Funding

Sine RetrotranspositionR01GM045668 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI DEININGER, PRESCOTT L. · 1993 to 2014
$4.2M
NIGMS NIH HHS R01 GM045668NIGMS NIH HHS R01GM45668
6 · The paper itself

Abstract

Alu elements are primate-specific repeats and comprise 11% of the human genome. They have wide-ranging influences on gene expression. Their contribution to genome evolution, gene regulation and disease is reviewed.

Indexed as

Gene Expression RegulationGenome, HumanAlu ElementsAnimalsBiological EvolutionDNA Copy Number VariationsGenetic VariationGenomic InstabilityHumansMutagenesis, InsertionalNucleic Acid ConformationPrimatesRetroelementsRetroelements

Identifiers

PMID22204421
PMCPMC3334610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.