ArticleJournal of women's health (2002)2012
Failed lactation and perinatal depression: common problems with shared neuroendocrine mechanisms?
Article in Journal of women's health (2002), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03638687 (Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers), which is not on this map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of behavioral interventions to improve maternal mental health and breastfeeding outcomes: a systematic review.International breastfeeding journal · 2022Pooled it
- Pooled it
- The effectiveness of interventions using relaxation therapy to improve breastfeeding outcomes: A systematic review.Maternal & child nutrition · 2018Pooled it
- Lactation-focused audio relaxation versus standard care for mothers of very preterm infants (the EXPRESS randomised clinical trial).Pediatric research · 2025Trial
- A randomized controlled trial of the Happy, Healthy, Loved personalized text-message program for new parent couples: impact on breastfeeding self-efficacy and mood.BMC pregnancy and childbirth · 2024Trial
- Effect of Acupoint Hot Compress on Postpartum Urinary Retention After Vaginal Delivery: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Perinatal Depression: Current Knowledge.Advances in experimental medicine and biology · 2026Review
- Investigation of the Relationship Between Weaning Readiness and Maternal Depression: Cross-Sectional Online Survey.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Fear of Childbirth Impairs Breastfeeding Success Independent of Mode of Birth.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2024Article
- Food and housing insecurity: do they affect the continuation of breastfeeding at four months of age?Journal of hunger & environmental nutrition · 2024Article
- Evaluation of obstetric outcomes for women in commuter versus non-commuter marriages: A comparative study.Journal of Taibah University Medical Sciences · 2022Article
- Article
- Dietary Intake of Polyphenols Enhances Executive/Attentional Functioning and Memory with an Improvement of the Milk Lipid Profile of Postpartum Women from Argentina.Journal of Intelligence · 2022Article
- Maternal Psychological Distress and Lactation and Breastfeeding Outcomes: a Narrative Review.Clinical therapeutics · 2022Review
- Exposure to environmental chemicals and perinatal psychopathology.Biochemical pharmacology · 2022Review
- Exploring the Prescribing Process of Domperidone for Low Milk Supply: A Qualitative Study Among Mothers, IBCLCs, and Family Doctors.Journal of human lactation : official journal of International Lactation Consultant Association · 2021Article
- Article
- Do Maternal Stress and Depressive Symptoms in Perinatal Period Predict the Lactation Mastitis Occurrence? A Retrospective Longitudinal Study in Greek Women.Diagnostics (Basel, Switzerland) · 2021Article
- A Comparative Review of the Extrinsic and Intrinsic Factors Regulating Lactose Synthesis.Journal of mammary gland biology and neoplasia · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In the early postpartum period, mother and infant navigate a critical neuroendocrine transition from pregnancy to lactation. Two major clinical problems that occur during this transition are failed lactation and perinatal mood disorders. These disorders often overlap in clinical settings. Failed lactation is common. Although all major medical organizations recommend 6 months of exclusive breastfeeding, only 13% of women in the United States achieve this recommendation. Perinatal mood disorders affect 10% of mothers, with substantial morbidity for mother and child. We hypothesize that shared neuroendocrine mechanisms contribute to both failed lactation and perinatal mood disorders. In this hypothesis article, we discuss data from both animal models and clinical studies that suggest neuroendocrine mechanisms that may underlie these two disorders. Research to elucidate the role of these underlying mechanisms may identify treatment strategies both to relieve perinatal depression and to enable women to achieve their infant feeding goals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.