Evidence map›Paper›PMID 22203760›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2012

Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside.

Vivek Subbiah, John Slopis, David S Hong, Leena M Ketonen, Jackson Hamilton, Ian E McCutcheon, Razelle Kurzrock

Open access · bronzeAbstract readClinical Trial, Phase I
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Current Understanding of Neurofibromatosis Type 1, 2, and Schwannomatosis.International journal of molecular sciences · 2021
    Review
  9. Review
  10. Review
  11. Essential signaling inJournal of thoracic disease · 2017
    Article
  12. Review
  13. The role of stem cells in benign tumors.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  14. Childhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2016
    Review
  15. The Conundrum of Genetic "Drivers" in Benign Conditions.Journal of the National Cancer Institute · 2016
    Review
  16. Article
  17. Article
  18. Article
  19. Inhibition of the phosphoinositide 3-kinase pathway for the treatment of patients with metastatic metaplastic breast cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2015
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vivek SubbiahThe University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. vsubbiah@mdanderson.org
John Slopis
David S Hong
Leena M Ketonen
Jackson Hamilton
Ian E McCutcheon
Razelle Kurzrock
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Phase I Studies of Targeted Anti-Cancer TherapiesU01CA062461 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YAO, JAMES C · 1994 to 2013
$7.2M
NCI NIH HHS 5 U01 CA062461NCI NIH HHS CA 016672NCI NIH HHS P30 CA016672NCI NIH HHS U01 CA062461
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Targeted TherapyAdolescentAdultAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBenzenesulfonatesBevacizumabChildChild, PreschoolDrug SynergismErlotinib HydrochlorideFemaleHumansIndolesAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedAntineoplastic AgentsBenzenesulfonatesBevacizumabErlotinib HydrochlorideIndolesMTOR protein, humanNiacinamidePhenylurea CompoundsPyridinesPyrrolesQuinazolinesSirolimusSorafenibSunitinibtemsirolimusTOR Serine-Threonine KinasesValproic AcidVascular Endothelial Growth Factor A

Identifiers

PMID22203760
PMCPMC3295556
OpenAlexW2074067653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.