Evidence map›Paper›PMID 22203597›Full record

ArticleAntimicrobial agents and chemotherapy2012

First report of the multidrug resistance gene cfr in Enterococcus faecalis of animal origin.

Yang Liu, Yang Wang, Congming Wu, Zhangqi Shen, Stefan Schwarz, Xiang-Dang Du, Lei Dai, Wanjiang Zhang, Qijing Zhang, Jianzhong Shen

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 131 citations in OpenAlex.

  1. The novel pseudo-compound transposon TnMicrobial genomics · 2026
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  7. Profiling Antibiotic Susceptibility among DistinctAntibiotics (Basel, Switzerland) · 2023
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  8. Ribosome-targeting antibiotics and resistanceRSC medicinal chemistry · 2023
    Review
  9. Vancomycin Resistance inMicroorganisms · 2022
    Review
  10. Review
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  13. Linezolid-ResistantFoods (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Detection and Antimicrobial Resistance ofVeterinary medicine international · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Pathogens (Basel, Switzerland) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Yang LiuKey Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Yang Wang
Congming Wu
Zhangqi Shen
Stefan Schwarz
Xiang-Dang Du
Lei Dai
Wanjiang Zhang
Qijing Zhang
Jianzhong Shen
China Agricultural University · CNIowa State University · USFriedrich-Loeffler-Institut · DEHenan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multiresistance gene cfr was identified for the first time in an Enterococcus faecalis isolate of animal origin. The 32,388-bp plasmid pEF-01, which carried the cfr gene, was sequenced completely. Three copies of the insertion sequence IS1216 were identified in pEF-01, and the detection of a cfr- and IS1216-containing amplicon by inverse PCR suggests that IS1216 may play a role in the dissemination of cfr by a recombination process.

Indexed as

AnimalsAnti-Bacterial AgentsBacterial ProteinsCattleCattle DiseasesChloramphenicolDNA, BacterialDNA Transposable ElementsDrug Resistance, Multiple, BacterialEnterococcus faecalisGene DosageGram-Positive Bacterial InfectionsMethyltransferasesMutagenesis, InsertionalPlasmidsPolymerase Chain ReactionAnti-Bacterial AgentsBacterial ProteinsChloramphenicolDNA, BacterialDNA Transposable ElementsflorfenicolMethyltransferasesThiamphenicol

Identifiers

PMID22203597
PMCPMC3294887
OpenAlexW2134214056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.