ArticleJournal of microbiology (Seoul, Korea)2011
Frequency of antibiotic resistance in Helicobacter pylori strains isolated from the northern population of Iran.
Article in Journal of microbiology (Seoul, Korea), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of clarithromycin-resistantPeerJ · 2023Pooled it
- Trial
- Evaluation of antibiotic resistance of Helicobacter pylori bacteria obtained from gastric biopsy samples: A cohort study.Annals of medicine and surgery (2012) · 2022Article
- Comparing the Effect of Two Low-dose and High-dose Four-drug Regimens of Furazolidone in EradicatingMiddle East journal of digestive diseases · 2021Article
- Genetic basis for metronidazole and clarithromycin resistance inInfection and drug resistance · 2019Article
- Comparison of Levofloxacin-Based, 10-day Sequential Therapy with 14-day Quadruple Therapy forMiddle East journal of digestive diseases · 2018Article
- Eradication ofMiddle East journal of digestive diseases · 2018Review
- Resistance ofWorld journal of gastroenterology · 2017Article
- Resistance to clarithromycin and gastroenterologist's persistence roles in nomination for Helicobacter pylori as high priority pathogen by World Health Organization.World journal of gastroenterology · 2017Article
- Clarithromycin versus Gemifloxacin in Quadruple Therapeutic Regimens forMiddle East journal of digestive diseases · 2017Article
- Management of Helicobacter pylori infections.BMC gastroenterology · 2016Article
- Vaccine against Helicobacter pylori: Inevitable approach.World journal of gastroenterology · 2016Review
- Helicobacter pylori and Gastric Cancer.Frontiers in medicine · 2016Article
- Prevalence of antibiotic resistance in Helicobacter pylori: A recent literature review.World journal of methodology · 2015Review
- How to Effectively Use Bismuth Quadruple Therapy: The Good, the Bad, and the Ugly.Gastroenterology clinics of North America · 2015Review
- Appropriate first-line regimens to combat Helicobacter pylori antibiotic resistance: an Asian perspective.Molecules (Basel, Switzerland) · 2015Review
- Clarithromycin vs. Gemifloxacin in Quadruple Therapy Regimens for Empiric Primary Treatment of Helicobacter pylori Infection: A Randomized Clinical Trial.Middle East journal of digestive diseases · 2015Article
- Helicobacter pylori in Iran: A systematic review on the antibiotic resistance.Iranian journal of basic medical sciences · 2015Review
- Comparison of quadruple and triple Furazolidone containing regimens on eradication of helicobacter pylori.Medical journal of the Islamic Republic of Iran · 2015Article
- Comparing the efficacy of four different protocols for eradicating of Helicobacter pylori infection in Ahvaz, southwest Iran.Przeglad gastroenterologiczny · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The purpose of this study was to evaluate the primary resistance rates of recent clinical Helicobacter pylori isolates to the most commonly used antibiotics in Iran. Two hundreds and ten patients presenting with gastric maladies between January and July of 2009 were enrolled in this study. Endoscopy was performed, and biopsy specimens were collected from each patient for subsequent bacterial culture of H. pylori. Single colony isolates from each patient were then used for antimicrobial susceptibility testing. The disk diffusion method was used to determine susceptibility patterns. One hundred and ninety-seven of the patients were H. pylori positive (93.8%). The rates of resistance to tetracycline, amoxicillin, ciprofloxacin, metronidazole, clarithromycin, and furizoladone were 37.1%, 23.9%, 34.5%, 65.5%, 45.2%, and 61.4%, respectively. A significant association between amoxicillin resistance and disease state (P<0.05) was identified. Furthermore, some double, triple, quadruple, and quintuple combinations of antibiotic resistance were found to be associated with disease state. This study evaluated the prevalence of H. pylori resistance to the most commonly prescribed antibiotics used in Iran and showed that resistance rates were generally higher than previously reported. This data adds to the growing body of evidence that suggests there is increasing antibiotic resistance among H. pylori isolates, which likely is responsible for the decreasing efficacy of anti-H. pylori therapy at the local and global level. Hence, there is a need for continued monitoring of resistance patterns, especially at the local level, and for incorporation of that information into treatment regimens for H. pylori infections.
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