ArticleJournal of microbiology (Seoul, Korea)2011
Complete genome of Leptospirillum ferriphilum ML-04 provides insight into its physiology and environmental adaptation.
Article in Journal of microbiology (Seoul, Korea), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 57 citations in OpenAlex.
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- Nucleotide- and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A Critical Review on the Recovery of Base and Critical Elements from Electronic Waste-Contaminated Streams Using Microbial Biotechnology.Applied biochemistry and biotechnology · 2023Review
- Recent progress in the application of omics technologies in the study of bio-mining microorganisms from extreme environments.Microbial cell factories · 2021Review
- Bioleaching of E-Waste: Influence of Printed Circuit Boards on the Activity of Acidophilic Iron-Oxidizing Bacteria.Frontiers in microbiology · 2021Article
- Homogeneous Cytochrome 579 Is an Octamer That Reacts Too Slowly With Soluble Iron to Be the Initial Iron Oxidase in the Respiratory Chain ofFrontiers in microbiology · 2021Article
- Microorganisms and Their Metabolic Capabilities in the Context of the Biogeochemical Nitrogen Cycle at Extreme Environments.International journal of molecular sciences · 2020Review
- Article
- Reconstruction of the Functional Ecosystem in the High Light, Low Temperature Union Glacier Region, Antarctica.Frontiers in microbiology · 2019Article
- In a quest for engineering acidophiles for biomining applications: challenges and opportunities.Genes · 2018Review
- Multi-omics Reveals the Lifestyle of the Acidophilic, Mineral-Oxidizing Model Species Leptospirillum ferriphilumApplied and environmental microbiology · 2018Article
- Pan-Genome Analysis Links the Hereditary Variation ofFrontiers in microbiology · 2018Article
- Codon usage bias reveals genomic adaptations to environmental conditions in an acidophilic consortium.PloS one · 2018Article
- Comparative Genomics Unravels the Functional Roles of Co-occurring Acidophilic Bacteria in Bioleaching Heaps.Frontiers in microbiology · 2017Article
- Article
- Putative bacterial interactions from metagenomic knowledge with an integrative systems ecology approach.MicrobiologyOpen · 2016Article
- Cobalamin Protection against Oxidative Stress in the Acidophilic Iron-oxidizing Bacterium Leptospirillum Group II CF-1.Frontiers in microbiology · 2016Article
- Draft genome sequence of chloride-tolerant Leptospirillum ferriphilum Sp-Cl from industrial bioleaching operations in northern Chile.Standards in genomic sciences · 2016Article
- Draft genome of iron-oxidizing bacterium Leptospirillum sp. YQP-1 isolated from a volcanic lake in the Wudalianchi volcano, China.Genomics data · 2015Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirillum ferriphilum has been identified as the dominant, moderately thermophilic, bioleaching microorganism in bioleaching processes. It is an acidic and chemolithoautrophic bacterium that gains electrons from ferrous iron oxidation for energy production and cell growth. Genetic information about this microorganism has been limited until now, which has hindered its further exploration. In this study, the complete genome of L. ferripilum ML-04 is sequenced and annotated. The bacterium has a single circular chromosome of 2,406,157 bp containing 2,471 coding sequences (CDS), 2 rRNA operons, 48 tRNA genes, a large number of mobile genetic elements and 2 genomic islands. In silico analysis shows L. ferriphilum ML-04 fixes carbon through a reductive citric acid (rTCA) cycle, and obtains nitrogen through ammonium assimilation. The genes related to "cell envelope biogenesis, outer membrane" (6.9%) and "DNA replication, recombination and repair" (5.6%) are abundant, and a large number of genes related to heavy metal detoxification, oxidative and acidic stress defense, and signal transduction pathways were detected. The genomic plasticity, plentiful cell envelope components, inorganic element metabolic abilities and stress response mechanisms found the base for this organism's survival in the bioleaching niche.
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