Trial reportInternational journal of colorectal disease2012
Sacral nerve modulation in the treatment of chronic pelvic pain.
Trial report in International journal of colorectal disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Efficacy and mechanisms of neuromodulation in the treatment of irritable bowel syndrome.Bioelectronic medicine · 2025Review
- Fluoroscopy-Guided Transgluteal Pudendal Nerve Block for Pudendal Neuralgia: A Retrospective Case Series.Journal of clinical medicine · 2024Article
- Spinal Cord Stimulation for Intractable Visceral Pain Originating from the Pelvic and Abdominal Region: A Narrative Review on a Possible New Indication for Patients with Therapy-Resistant Pain.Journal of pain research · 2024Review
- Sacral neuromodulation in endometriosis - A promising treatment option for chronic pelvic pain.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Current advances in neuromodulation techniques in urology practices: A review of literature.Turkish journal of urology · 2021Article
- Outcomes of sacral neuromodulation for chronic pelvic pain: a Finnish national multicenter study.Techniques in coloproctology · 2020Article
- Pelvic pain rehabilitation.Turkish journal of physical medicine and rehabilitation · 2018Review
- Neuromodulation for Pelvic and Urogenital Pain.Brain sciences · 2018Review
- Role of sacral neuromodulation in modern urogynaecology practice: a review of recent literature.International urogynecology journal · 2018Review
- Neuromodulation for Chronic Pelvic Pain.Current urology reports · 2018Review
- Sacral Neuromodulation: Foray into Chronic Pelvic Pain in End Stage Endometriosis.Case reports in neurological medicine · 2017Article
- Axotomy of tributaries of the pelvic and pudendal nerves induces changes in the neurochemistry of mouse dorsal root ganglion neurons and the spinal cord.Brain structure & function · 2016Article
- Sacral neuromodulation for bowel dysfunction: a consensus statement from the Italian group.Techniques in coloproctology · 2014Article
- [Chronic pelvic pain syndrome: neurostimulation, neuromodulation and acupuncture].Der Urologe. Ausg. A · 2012Article
- Article
- Analgesic efficacy of sacral neuromodulation for chronic pelvic cancer pain.Saudi journal of anaesthesiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic pelvic pain is a common condition that significantly compromises the quality of life of affected patients. Unfortunately, despite treatment procedures, the results are often ineffective and symptoms persist for years. For these reasons, the search for less aggressive treatment options with fewer negative consequences leading to minimally invasive techniques was conducted.
objectiveThe aim of the present study was to evaluate the efficacy of sacral nerve modulation in the treatment of chronic pelvic pain. Moreover, we aimed to identify potential predictors of positive results of sacral neuromodulation through the comparison between failed and successful patients. PATIENTS: From January 2004 to December 2009, all consecutive patients suffering from chronic pelvic pain and tested for sacral nerve modulation in three pelvic floor dedicated centers were evaluated. Severity of symptoms were analyzed by a visual analog scale (VAS)
resultsTwenty-seven patients (2 males; mean age, 53 years) were tested for sacral nerve modulation in the screening period and were included in the present study. The mean duration of pain was 51 months (range, 10-132 months). The mean preoperative VAS was 7.8 (range, 5-10). Previous pelvic surgery was reported in 18 patients (66.5%). Sixteen patients (59%) fulfil the successful criteria and were definitively implanted. The mean follow-up was 37 months (range, 12-71 months). The mean preoperative VAS was 8.1 (range, 6-8) and decreased to 2.1 ± 1.2 at 6-month follow-up (p < 0.0001), to 2.1 ± 1.1 at 12 months (16 patients), to 2.0 ± 1.2 at 24 months (13 patients), to 2.3 ± 1.4 at 36 months (9 patients), to 2.1 ± 1.5 at 48 months (5 patients), and to 1.9 ± 1.3 at 60 months (3 patients).
conclusionsSacral neuromodulation proved to be effective in the treatment of some patients affected by chronic pelvic pain, and the effect persists over time. A positive screening phase and a positive response to gabapentin or pregabalin showed to be predictors of a successful response. Multiple localizations of pelvic pain and pain occurred after stapler surgery seem to be negative factors for the success of the treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.