ReviewFrontiers in bioscience (Elite edition)2012
The emerging roles of prohibitins in folliculogenesis.
Review in Frontiers in bioscience (Elite edition), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- hUMSCs restore ovarian function in POI mice by regulating GSK3β-mediated mitochondrial dynamic imbalances in theca cells.Scientific reports · 2024Article
- Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer.BMC genomics · 2023Article
- Mycobacterial protein PE_PGRS30 induces macrophage apoptosis through prohibitin 2 mitochondrial function interference.Frontiers in microbiology · 2023Article
- Prohibitin 2/PHB2 in Parkin-Mediated Mitophagy: A Potential Therapeutic Target for Non-Small Cell Lung Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- A novel prognostic marker and immunogenic membrane antigen: prohibitin (PHB) in pancreatic cancer.Clinical and translational gastroenterology · 2018Article
- Association of 758 G/A polymorphism of 3'untranslated region of prohibitin with risk of gastric cancer.Journal of clinical laboratory analysis · 2018Article
- Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.Oncogene · 2017Article
- Molecular identification and characterization of prohibitin from Echinococcus granulosus.Parasitology research · 2016Article
- Prohibitin( PHB) roles in granulosa cell physiology.Cell and tissue research · 2016Review
- Prohibitins role in cellular survival through Ras-Raf-MEK-ERK pathway.Journal of cellular physiology · 2014Review
- Association of prohibitin-1 and 2 with oxidative stress in rats with renal interstitial fibrosis.Molecular biology reports · 2014Article
- Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins.Apoptosis : an international journal on programmed cell death · 2013Article
- Prohibitin is associated with antioxidative protection in hypoxia/reoxygenation-induced renal tubular epithelial cell injury.Scientific reports · 2013Article
- Gonadotropin-releasing hormone-regulated prohibitin mediates apoptosis of the gonadotrope cells.Molecular endocrinology (Baltimore, Md.) · 2013Article
- Follicular stage-dependent regulation of apoptosis and steroidogenesis by prohibitin in rat granulosa cells.Journal of ovarian research · 2013Article
- Prohibitin attenuates oxidative stress and extracellular matrix accumulation in renal interstitial fibrosis disease.PloS one · 2013Article
- Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells.PloS one · 2012Article
- Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells.Life sciences · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Prohibitins are members of a highly conserved eukaryotic protein family containing the stomatin/prohibitin/flotillin/HflK/C (SPFH) domain (also known as the prohibitin (PHB) domain) found in divergent species from prokaryotes to eukaryotes. Prohibitins are found in unicellular eukaryotes, fungi, plants, animals and humans. Prohibitins are ubiquitously expressed and present in multiple cellular compartments including the mitochondria, nucleus, and the plasma membrane, and shuttles between the mitochondria, cytosol and nucleus. Multiple functions have been attributed to the mitochondrial and nuclear prohibitins, including cellular differentiation, anti-proliferation, and morphogenesis. In the present review, we focus on the recent developments in prohibitins research related to folliculogenesis. Based on current research findings, the data suggest that these molecules play important roles in modulating specific responses of granulose cells to follicle stimulating hormone (FSH) by acting at multiple levels of the FSH signal transduction pathway. Understanding the molecular mechanisms by which the intracellular signaling pathways utilize prohibitins in governing folliculogenesis is likely to result in development of strategies to overcome fertility disorders and suppress ovarian cancer growth.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.