ReviewFrontiers in bioscience (Landmark edition)2012
LINEs, SINEs and other retroelements: do birds of a feather flock together?
Review in Frontiers in bioscience (Landmark edition), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Selection for Molecularly Complementary Modules (MCMs) Drives the Origins and Evolution of Pleiofunctional, Epistatic Interactomes (PEIs).Life (Basel, Switzerland) · 2026Review
- Platy-1 SINEs from Thirteen Diverse Genomes Reveal Callithrichidae Unique Amplification, RecentGenes · 2026Article
- Analysis of RNA Transcribed by RNA Polymerase III from B2 SINEs in Mouse Cells.Non-coding RNA · 2025Article
- Article
- Inhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats.Nature communications · 2024Article
- Retrotransposon LINE-1 bodies in the cytoplasm of piRNA-deficient mouse spermatocytes: Ribonucleoproteins overcoming the integrated stress response.PLoS genetics · 2023Article
- The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice.PLoS genetics · 2023Article
- Tail Wags Dog's SINE: Retropositional Mechanisms of Can SINE Depend on Its A-Tail Structure.Biology · 2022Article
- Transposable Element Populations Shed Light on the Evolutionary History of Wheat and the Complex Co-Evolution of Autonomous and Non-Autonomous Retrotransposons.Advanced genetics (Hoboken, N.J.) · 2022Article
- A Model-Driven Quantitative Analysis of Retrotransposon Distributions in the Human Genome.Genome biology and evolution · 2020Article
- Review
- Piwi-interacting RNAs (piRNAs) and cancer: Emerging biological concepts and potential clinical implications.Biochimica et biophysica acta. Reviews on cancer · 2019Review
- Viruses and immunosenescence - more players in the game.Immunity & ageing : I & A · 2019Review
- Identification of transposable elements fused in the exonic region of the olive flounder genome.Genes & genomics · 2018Article
- Comparative Genomics Reveals Two Major Bouts of Gene Retroposition Coinciding with Crucial Periods of Symbiodinium Evolution.Genome biology and evolution · 2017Article
- Identification of RNA Polymerase III-Transcribed SINEs at Single-Locus Resolution from RNA Sequencing Data.Non-coding RNA · 2017Review
- Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition.Genetics · 2017Article
- Whole-genome expression analysis of mammalian-wide interspersed repeat elements in human cell lines.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Analysis of the human immunodeficiency virus-1 RNA packageome.RNA (New York, N.Y.) · 2016Article
- Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits.Nucleic acids research · 2015Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Mobile elements account for almost half of the mass of the human genome. Only the retroelements from the non-LTR (long terminal repeat) retrotransposon family, which include the LINE-1 (L1) and its non-autonomous partners, are currently active and contributing to new insertions. Although these elements seem to share the same basic amplification mechanism, the activity and success of the different types of retroelements varies. For example, Alu-induced mutagenesis is responsible for the majority of the documented instances of human disease induced by insertion of retroelements. Using copy number in mammals as an indicator, some SINEs have been vastly more successful than other retroelements, such as the retropseudogenes and even L1, likely due to differences in post-insertion selection and ability to overcome cellular controls. SINE and LINE integration can be differentially influenced by cellular factors, indicating some differences between in their amplification mechanisms. We focus on the known aspects of this group of retroelements and highlight their similarities and differences that may significantly influence their biological impact.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.