Evidence map›Paper›PMID 22201785›Full record

ReviewFrontiers in bioscience (Landmark edition)2012

Mitotic checkpoint control and chromatin remodeling.

Yixin Yao, Wei Dai

Open access · bronzeAbstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yixin YaoDepartment of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA.
Wei Dai
New York University · US

Funding

RESEARCH IN ENVIRONMENTAL HEALTH SCIENCES (CENTER GRANT)P30ES000260 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 1985 to 2020
$26.1M
Water/sediment &model &criteria for arsenic &chromeP42ES010344 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COSTA, MAX · 2000 to 2010
$15.0M
Molecular mechanisms underlying chromosomal instability and aneuploidyR01CA090658 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DAI, WEI · 2001 to 2012
$2.9M
PROTEIN SER/THR KINASE PRK AND CELL CYCLE PROGRESSIONR01CA074229 · NCI · UNIVERSITY OF CINCINNATI · PI DAI, WEI · 1998 to 2007
$2.1M
Mechanisms of arsenic-induced chromosomal instability and carcinogenesisR01ES020591 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DAI, WEI · 2012 to 2016
$2.0M
Plk3, A New Player In The Hypoxia Regulatory Networ.R01CA150512 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DAI, WEI · 2011 to 2015
$1.6M
Novel mouse colon cancer models and chemopreventionR01CA113349 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DAI, WEI · 2006 to 2010
$1.5M
NCI NIH HHS CA090658NCI NIH HHS CA113349NCI NIH HHS R01 CA074229NCI NIH HHS R01 CA090658NCI NIH HHS R01 CA113349NCI NIH HHS R01 CA150512NIEHS NIH HHS ES000260NIEHS NIH HHS ES010344NIEHS NIH HHS P30 ES000260NIEHS NIH HHS P42 ES010344NIEHS NIH HHS R01 ES020591
6 · The paper itself

Abstract

In order to maintain chromosomal stability during cell division, eukaryotic cells have evolved a number of surveillance mechanisms termed checkpoints. These checkpoints monitor the completion of essential molecular and cellular processes of one stage before entering another. The spindle checkpoint watches the bi-orientation attachment of spindle microtubules to all condensed chromosomes before initiation of nuclear division during mitosis. Histones are subject to a number of post-translational modifications during the cell cycle, which may in turn modify or facilitate cell cycle progression. Recent studies suggest that mitotic proteins including Bub1 and Sgo1 that are involved in the spindle checkpoint also play a major role in the regulation of histone modifications and chromatin remodeling. This mini-review summarizes emerging information about the new role of spindle checkpoint proteins in chromatin remodeling.

Indexed as

AnimalsCell Cycle ProteinsChromatin Assembly and DisassemblyHumansModels, BiologicalM Phase Cell Cycle CheckpointsProtein IsoformsProtein Serine-Threonine KinasesBUB1 protein, humanBub1 spindle checkpoint proteinCell Cycle ProteinsProtein IsoformsProtein Serine-Threonine Kinases

Identifiers

PMID22201785
PMCPMC3762472
OpenAlexW2006205736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.