Evidence map›Paper›PMID 22201532›Full record

ReviewMolecular imaging2011

Techniques for molecular imaging probe design.

Fred Reynolds, Kimberly A Kelly

Abstract readReview
In one paragraph

Review in Molecular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Molecular imaging in the era of personalized medicine.Journal of pathology and translational medicine · 2015
    Review
  10. Article
  11. Molecular imaging probe development: a chemistry perspective.American journal of nuclear medicine and molecular imaging · 2012
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fred ReynoldsRobert M. Berne Cardiovascular Research Center and Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Kimberly A Kelly

Funding

Development of Molecularly Targeted Imaging Agents for KRAS activity in vivoR01EB010023 · NIBIB · UNIVERSITY OF VIRGINIA · PI EL-BARDEESY, NABEEL, KELLY, KIMBERLY A. · 2010 to 2013
$1.4M
Development of Molecularly Targeted Imaging Agents for Early Detection of PDACR01CA137071 · NCI · UNIVERSITY OF VIRGINIA · PI KELLY, KIMBERLY A. · 2008 to 2012
$1.3M
NCI NIH HHS R01 CA137071NIBIB NIH HHS R01 EB010023
6 · The paper itself

Abstract

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology--all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.

Indexed as

Molecular Probe TechniquesAnimalsAntibodiesDNAHumansMolecular ImagingMolecular ProbesPeptidesRNAAntibodiesDNAMolecular ProbesPeptidesRNA

Identifiers

PMID22201532
PMCPMC3224676

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.