ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2012
Genomics of isolation in hybrids.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 131 citations in OpenAlex.
- Comparative analysis of multiple hybrid zones ofPlant diversity · 2025Article
- A Next Generation of Hierarchical Bayesian Analyses of Hybrid Zones Enables Model-Based Quantification of Variation in Introgression in R.Ecology and evolution · 2024Article
- Quantitative Analyses of Coupling in Hybrid Zones.Cold Spring Harbor perspectives in biology · 2023Review
- Genomic clines across the species boundary between a hybrid pine and its progenitor in the eastern Tibetan Plateau.Plant communications · 2023Article
- Two transects reveal remarkable variation in gene flow on opposite ends of a European toad hybrid zone.Heredity · 2023Article
- Experimentally testing mate preference in an avian system with unidirectional bill color introgression.Ecology and evolution · 2023Article
- Limited movement of an avian hybrid zone in relation to regional variation in magnitude of climate change.Molecular ecology · 2022Article
- Widespread genomic signatures of reproductive isolation and sex-specific selection in the Eastern Yellow Robin, Eopsaltria australis.G3 (Bethesda, Md.) · 2022Article
- Complex introgression among three diverged largemouth bass lineages.Evolutionary applications · 2021Article
- ClineHelpR: an R package for genomic cline outlier detection and visualization.BMC bioinformatics · 2021Article
- Spatial population genetics in heavily managed species: Separating patterns of historical translocation from contemporary gene flow in white-tailed deer.Evolutionary applications · 2021Article
- Morning glory species co-occurrence is associated with asymmetrically decreased and cascading reproductive isolation.Evolution letters · 2021Article
- Selection on a small genomic region underpins differentiation in multiple color traits between two warbler species.Evolution letters · 2020Article
- Recent hybrids recapitulate ancient hybrid outcomes.Nature communications · 2020Article
- Tracing the footprints of a moving hybrid zone under a demographic history of speciation with gene flow.Evolutionary applications · 2020Article
- Multiple forms of selection shape reproductive isolation in a primate hybrid zone.Molecular ecology · 2019Article
- Demographic history influences spatial patterns of genetic diversityin recently expanded coyote (Canis latrans) populations.Heredity · 2018Article
- Adaptive introgression: a plant perspective.Biology letters · 2018Review
- Inconsistent reproductive isolation revealed by interactions betweenEvolution letters · 2017Article
- Insight into the roles of selection in speciation from genomic patterns of divergence and introgression in secondary contact in venomous rattlesnakes.Ecology and evolution · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrid zones are common in nature and can offer critical insights into the dynamics and components of reproductive isolation. Hybrids between diverged lineages are particularly informative about the genetic architecture of reproductive isolation, because introgression in an admixed population is a direct measure of isolation. In this paper, we combine simulations and a new statistical model to determine the extent to which different genetic architectures of isolation leave different signatures on genome-level patterns of introgression. We found that reproductive isolation caused by one or several loci of large effect caused greater heterogeneity in patterns of introgression than architectures involving many loci with small fitness effects, particularly when isolating factors were closely linked. The same conditions that led to heterogeneous introgression often resulted in a reasonable correspondence between outlier loci and the genetic loci that contributed to isolation. However, demographic conditions affected both of these results, highlighting potential limitations to the study of the speciation genomics. Further progress in understanding the genomics of speciation will require large-scale empirical studies of introgression in hybrid zones and model-based analyses, as well as more comprehensive modelling of the expected levels of isolation with different demographies and genetic architectures of isolation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.