Evidence map›Paper›PMID 22200984›Full record

ArticleTransgenic research2012

Field testing, gene flow assessment and pre-commercial studies on transgenic Solanum tuberosum spp. tuberosum (cv. Spunta) selected for PVY resistance in Argentina.

Fernando Bravo-Almonacid, Valeria Rudoy, Bjorn Welin, María Eugenia Segretin, María Cecilia Bedogni, Fabiana Stolowicz, Marcelo Criscuolo, Marcelo Foti, Maximiliano Gomez, Mariana López and 5 more

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Article in Transgenic research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Fernando Bravo-AlmonacidInstituto de Investigaciones en Ingeniería Genética y Biología Molecular (CONICET), Vuelta de Obligado 2490 (C1428ADN), Buenos Aires, Argentina. fbravo@dna.uba.ar
Valeria Rudoy
Bjorn Welin
María Eugenia Segretin
María Cecilia Bedogni
Fabiana Stolowicz
Marcelo Criscuolo
Marcelo Foti
Maximiliano Gomez
Mariana López
Germán Serino
Silvia Cabral
Cristina Dos Santos
Marcelo Huarte
Alejandro Mentaberry
Experimental Medicine and Biology Institute · ARNational Agricultural Technology Institute · ARConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solanum tuberosum ssp. tuberosum (cv. Spunta) was transformed with a chimeric transgene containing the Potato virus Y (PVY) coat protein (CP) sequence. Screening for PVY resistance under greenhouse conditions yielded over 100 independent candidate lines. Successive field testing of selected lines allowed the identification of two genetically stable PVY-resistant lines, SY230 and SY233, which were further evaluated in field trials at different potato-producing regions in Argentina. In total, more than 2,000 individuals from each line were tested along a 6-year period. While no or negligible PVY infection was observed in the transgenic lines, infection rates of control plants were consistently high and reached levels of up to 70-80%. Parallel field studies were performed in virus-free environments to assess the agronomical performance of the selected lines. Tubers collected from these assays exhibited agronomical traits and biochemical compositions indistinguishable from those of the non-transformed Spunta cultivar. In addition, an interspecific out-crossing trial to determine the magnitude of possible natural gene flow between transgenic line SY233 and its wild relative Solanum chacoense was performed. This trial yielded negative results, suggesting an extremely low probability for such an event to occur.

Indexed as

Disease ResistanceGene FlowAgrobacterium tumefaciensArgentinaCapsid ProteinsCrops, AgriculturalCrosses, GeneticGenetic VectorsPlant DiseasesPlants, Genetically ModifiedPotyvirusRecombinant Fusion ProteinsSolanaceous AlkaloidsSolanum tuberosumTransformation, GeneticTransgenesCapsid Proteinscoat protein, Potato virus YRecombinant Fusion ProteinsSolanaceous Alkaloids

Identifiers

PMID22200984
OpenAlexW2011860422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.