ArticlePersonalized medicine2011
Genomic information as a behavioral health intervention: can it work?
Article in Personalized medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of communicating the genetic risk of cardiometabolic disorders on motivation and actual engagement in preventative lifestyle modification and clinical outcome: a systematic review and meta-analysis of randomised controlled trials.The British journal of nutrition · 2016Pooled it
- Proof of Concept of a Personalized Genetic Risk Tool to Promote Smoking Cessation: High Acceptability and Reduced Cigarette Smoking.Cancer prevention research (Philadelphia, Pa.) · 2021Trial
- Interest and informational preferences regarding genomic testing for modest increases in colorectal cancer risk.Public health genomics · 2014Trial
- Disclosure of genetic information and change in dietary intake: a randomized controlled trial.PloS one · 2014Trial
- Trial
- Returning personal genetic information on susceptibility to arsenic toxicity to research participants in Bangladesh.Environmental research · 2024Article
- Genomic medicine to reduce tobacco and related disorders: Translation to precision prevention and treatment.Addiction neuroscience · 2023Article
- Direct-to-Consumer Genetic Testing in Korea: Current Status and Significance in Clinical Nutrition.Clinical nutrition research · 2021Review
- Priority of Risk (But Not Perceived Magnitude of Risk) Predicts Improved Sun-Protection Behavior Following Genetic Counseling for Familial Melanoma.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Article
- Developing community-based health education strategies with family history: Assessing the association between community resident family history and interest in health education.Social science & medicine (1982) · 2021Article
- Effects of health literacy skills, educational attainment, and level of melanoma risk on responses to personalized genomic testing.Patient education and counseling · 2021Article
- Genetic determinants of beverage consumption: Implications for nutrition and health.Advances in food and nutrition research · 2019Review
- Lung cancer and family-centered patient concerns.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Article
- Behavioural changes, sharing behaviour and psychological responses after receiving direct-to-consumer genetic test results: a systematic review and meta-analysis.Journal of community genetics · 2018Review
- Does personal genome testing drive service utilization in an adult preventive medicine clinic?Journal of community genetics · 2017Article
- Diet and exercise changes following direct-to-consumer personal genomic testing.BMC medical genomics · 2017Article
- Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016Article
- Toward clinical genomics in everyday medicine: perspectives and recommendations.Expert review of molecular diagnostics · 2016Article
- The Human Genome Project, and recent advances in personalized genomics.Risk management and healthcare policy · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Individuals can now obtain their personal genomic information via direct-to-consumer genetic testing, but what, if any, impact will this have on their lifestyle and health? A recent longitudinal cohort study of individuals who underwent consumer genome scanning found minimal impacts of testing on risk-reducing lifestyle behaviors, such as diet and exercise. These results raise an important question: is personal genomic information likely to beneficially impact public health through motivation of lifestyle behavioral change? In this article, we review the literature on lifestyle behavioral change in response to genetic testing for common disease susceptibility variants. We find that only a few studies have been carried out, and that those that have been done have yielded little evidence to suggest that the mere provision of genetic information alone results in widespread changes in lifestyle health behaviors. We suggest that further study of this issue is needed, in particular studies that examine response to multiplex testing for multiple genetic markers and conditions. This will be critical as we anticipate the wide availability of whole-genome sequencing and more comprehensive phenotyping of individuals. We also note that while simple communication of genomic information and disease susceptibility may be sufficient to catalyze lifestyle changes in some highly motivated groups of individuals, for others, additional strategies may be required to prompt changes, including more sophisticated means of risk communication (e.g., in the context of social norm feedback) either alone or in combination with other promising interventions (e.g., real-time wireless health monitoring devices).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.