Evidence map›Paper›PMID 22199380›Full record

ArticleBriefings in bioinformatics2012

Probe mapping across multiple microarray platforms.

Jeffrey D Allen, Siling Wang, Min Chen, Luc Girard, John D Minna, Yang Xie, Guanghua Xiao

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
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  6. Article
  7. Crosstalk analysis of dysregulated pathways in preeclampsia.Experimental and therapeutic medicine · 2019
    Article
  8. Article
  9. A Novel Method to Identify Differential Pathways in Hippocampus Alzheimer's Disease.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  10. Article
  11. Article
  12. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey D AllenUT Southwestern Medical Center, Dallas, TX 75390, USA.
Siling Wang
Min Chen
Luc Girard
John D Minna
Yang Xie
Guanghua Xiao

Funding

UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GIBBONS, DON LYNN · 1996 to 2024
$57.4M
Predicting Adjuvant Chemotherapy Response in Lung CancerR01CA152301 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI XIE, YANG · 2010 to 2014
$1.5M
Secondary Data Analyses for Substance Abuse ResearchR33DA027592 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI XIAO, GUANGHUA · 2011 to 2012
$622k
NCI NIH HHS 5R01CA152301NCI NIH HHS P50 CA070907NCI NIH HHS P50CA70907NIDA NIH HHS 4R33DA027592NIDA NIH HHS R33 DA027592
6 · The paper itself

Abstract

Access to gene expression data has become increasingly common in recent years; however, analysis has become more difficult as it is often desirable to integrate data from different platforms. Probe mapping across microarray platforms is the first and most crucial step for data integration. In this article, we systematically review and compare different approaches to map probes across seven platforms from different vendors: U95A, U133A and U133 Plus 2.0 from Affymetrix, Inc.; HT-12 v1, HT-12v2 and HT-12v3 from Illumina, Inc.; and 4112A from Agilent, Inc. We use a unique data set, which contains 56 lung cancer cell line samples-each of which has been measured by two different microarray platforms-to evaluate the consistency of expression measurement across platforms using different approaches. Based on the evaluation from the empirical data set, the BLAST alignment of the probe sequences to a recent revision of the Transcriptome generated better results than using annotations provided by Vendors or from Bioconductor's Annotate package. However, a combination of all three methods (deemed the 'Consensus Annotation') yielded the most consistent expression measurement across platforms. To facilitate data integration across microarray platforms for the research community, we develop a user-friendly web-based tool, an API and an R package to map data across different microarray platforms from Affymetrix, Illumina and Agilent. Information on all three can be found at http://qbrc.swmed.edu/software/probemapper/.

Indexed as

SoftwareDatabases, GeneticGene Expression ProfilingInternetOligonucleotide Array Sequence Analysis

Identifiers

PMID22199380
PMCPMC3431719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.