ReviewCurrent rheumatology reports2012
Genetics and mechanisms of crystal deposition in calcium pyrophosphate deposition disease.
Review in Current rheumatology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 50 citations in OpenAlex.
- Imaging approach to deposition and neurogenic arthropathies.Japanese journal of radiology · 2025Review
- A Narrative Review of Chondrocalcinosis: Clinical Presentation, Diagnosis, and Therapies.Cureus · 2024Review
- Selective pyrophosphate detection via metal complexes.iRadiology · 2023Article
- Inorganic Pyrophosphatase-Nanodiamond Conjugates Hydrolyze Pyrophosphate in Human Synovial Fluid.ACS omega · 2020Article
- Bioinspired extracellular vesicles embedded with black phosphorus for molecular recognition-guided biomineralization.Nature communications · 2019Article
- A novel highly fluorescent S, N, O co-doped carbon dots for biosensing and bioimaging of copper ions in live cells.RSC advances · 2018Article
- High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor.Chemical science · 2018Article
- Mast Cell Mediators Inhibit Osteoblastic Differentiation and Extracellular Matrix Mineralization.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2017Article
- Unilateral anterior crossbite induces aberrant mineral deposition in degenerative temporomandibular cartilage in rats.Osteoarthritis and cartilage · 2016Article
- Construction of a Turn Off-On-Off Fluorescent System Based on Competitive Coordination of CuJournal of analytical methods in chemistry · 2016Article
- Monoarticular hip involvement in pseudogout.Case reports in rheumatology · 2015Article
- [Chondrocalcinosis due to calcium pyrophosphate deposition (CPPD). From incidental radiographic findings to CPPD crystal arthritis].Zeitschrift fur Rheumatologie · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium pyrophosphate deposition (CPPD) disease (common in older adults) can be asymptomatic, associated with osteoarthritis, or can present as acute/chronic inflammatory arthritis. Due to the phenotypic complexity of CPPD, the European League Against Rheumatism (EULAR) recently made recommendations on terminology, diagnosis, and management based on available research evidence and expert consensus. There are no disease-modifying treatments for CPPD disease, and therapy remains nonspecific with the use of anti-inflammatory and analgesic drugs. For years, it has been known that inorganic phosphate and pyrophosphate regulate the formation of CPP or hydroxyapatite crystals. The discovery of ANKH (human homologue of progressive ankylosis) mutations in familial CPPD disease confirmed the importance of phosphate/pyrophosphate homeostasis in CPPD, with ANKH being a regulator of inorganic pyrophosphate transport. Despite progress in our understanding of the function of ANKH, much remains to be investigated. This review summarizes the genetic basis of this disease and focuses on the challenges of research in this area.
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