ArticleFly
A novel genetic tool for clonal analysis of fourth chromosome mutations.
Article in Fly. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- The KRÜPPEL-like transcription factor DATILÓGRAFO is required in specific cholinergic neurons for sexual receptivity in Drosophila females.PLoS biology · 2014Article
- Genetic analysis of mate discrimination in Drosophila simulans.Evolution; international journal of organic evolution · 2013Article
- Calcium and egg activation in Drosophila.Cell calcium · 2013Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The fourth chromosome of Drosophila remains one of the most intractable regions of the fly genome to genetic analysis. The main difficulty posed to the genetic analyses of mutations on this chromosome arises from the fact that it does not undergo meiotic recombination, which makes recombination mapping impossible, and also prevents clonal analysis of mutations, a technique which relies on recombination to introduce the prerequisite recessive markers and FLP-recombinase recognition targets (FRT). Here we introduce a method that overcomes these limitations and allows for the generation of single Minute haplo-4 clones of any fourth chromosome mutant gene in tissues of developing and adult flies.
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