ArticleCurrent biology : CB2012
A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence in sticklebacks.
Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.
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Who cites it
108 citing papers in PubMed, 248 citations in OpenAlex.
- Two Genetically Distinct Lineages in Galician Populations of the Three-Spined Stickleback (Ecology and evolution · 2026Article
- Multiple modes of selection underlie repeated and human-mediated adaptation in a formerly migratory fish.Molecular biology and evolution · 2026Article
- Rapid and repeated evolution of myosin copy number in threespine stickleback.Current biology : CB · 2026Article
- Article
- Rapid and repeated evolution of myosin copy number in threespine stickleback.bioRxiv : the preprint server for biology · 2025Article
- Coexistence in Sympatry With Gene Flow Before Speciation Has Completed.Molecular ecology · 2025Article
- A species interaction kick-starts ecological speciation in allopatry.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Adaptation to Freshwater in Allis Shad Involved a Combination of Genomic and Epigenomic Changes.Journal of molecular evolution · 2025Article
- Mate choice in the brain: species differ in how male traits 'turn on' gene expression in female brains.Proceedings. Biological sciences · 2024Article
- On the Origins of Phenotypic Parallelism in Benthic and Limnetic Stickleback.Molecular biology and evolution · 2023Article
- Hybridization is strongly constrained by salinity during secondary contact between silverside fishes (Odontesthes, Atheriniformes).Heredity · 2022Article
- Salinity-induced transcriptome profiles in marine and freshwater threespine stickleback after an abrupt 6-hour exposure.Ecology and evolution · 2022Article
- Evolution of stickleback spines through independent cis-regulatory changes at HOXDB.Nature ecology & evolution · 2022Article
- Genome-wide species delimitation analyses of a silverside fish species complex in central Mexico indicate taxonomic over-splitting.BMC ecology and evolution · 2022Article
- Convergent copy number increase of genes associated with freshwater colonization in fishes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Genomic changes underlying repeated niche shifts in an adaptive radiation.Evolution; international journal of organic evolution · 2022Article
- Heterosis counteracts hybrid breakdown to forestall speciation by parallel natural selection.Proceedings. Biological sciences · 2022Article
- Pleiotropy facilitates parallel adaptation in sticklebacks.Molecular ecology · 2022Article
- The maintenance of standing genetic variation: Gene flow vs. selective neutrality in Atlantic stickleback fish.Molecular ecology · 2022Article
- Genome-Environment Associations, an Innovative Tool for Studying Heritable Evolutionary Adaptation in Orphan Crops and Wild Relatives.Frontiers in genetics · 2022Review
48 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
Abstract
Genes underlying repeated adaptive evolution in natural populations are still largely unknown. Stickleback fish (Gasterosteus aculeatus) have undergone a recent dramatic evolutionary radiation, generating numerous examples of marine-freshwater species pairs and a small number of benthic-limnetic species pairs found within single lakes [1]. We have developed a new genome-wide SNP genotyping array to study patterns of genetic variation in sticklebacks over a wide geographic range, and to scan the genome for regions that contribute to repeated evolution of marine-freshwater or benthic-limnetic species pairs. Surveying 34 global populations with 1,159 informative markers revealed substantial genetic variation, with predominant patterns reflecting demographic history and geographic structure. After correcting for geographic structure and filtering for neutral markers, we detected large repeated shifts in allele frequency at some loci, identifying both known and novel loci likely contributing to marine-freshwater and benthic-limnetic divergence. Several novel loci fall close to genes implicated in epithelial barrier or immune functions, which have likely changed as sticklebacks adapt to contrasting environments. Specific alleles differentiating sympatric benthic-limnetic species pairs are shared in nearby solitary populations, suggesting an allopatric origin for adaptive variants and selection pressures unrelated to sympatry in the initial formation of these classic vertebrate species pairs.
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Registered trials
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