ReviewCurrent opinion in cell biology2012
Multiscale dynamics in nucleocytoplasmic transport.
Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Structural anisotropy results in mechano-directional transport of proteins across nuclear pores.Nature physics · 2024Article
- Transcription factor dynamics in plants: Insights and technologies for in vivo imaging.Plant physiology · 2022Review
- Multifunctionality of F-rich nucleoporins.Biochemical Society transactions · 2020Review
- The mechanical stability of proteins regulates their translocation rate into the cell nucleus.Nature physics · 2019Article
- The nuclear pore complex core scaffold and permeability barrier: variations of a common theme.Current opinion in cell biology · 2017Review
- Nuclear pores enable sustained perinuclear calcium oscillations.BMC systems biology · 2016Article
- The Multiple Faces of Disordered Nucleoporins.Journal of molecular biology · 2016Review
- Combining Spinach-tagged RNA and gene localization to image gene expression in live yeast.Nature communications · 2015Article
- Nuclear pore complex protein sequences determine overall copolymer brush structure and function.Biophysical journal · 2014Article
- How cells get the message: dynamic assembly and function of mRNA-protein complexes.Nature reviews. Genetics · 2013Review
- Arabidopsis TRANSCURVATA1 encodes NUP58, a component of the nucleopore central channel.PloS one · 2013Article
- Physical motif clustering within intrinsically disordered nucleoporin sequences reveals universal functional features.PloS one · 2013Article
- Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions.Nature reviews. Molecular cell biology · 2012Review
- Experimental approaches for addressing fundamental biological questions in living, functioning cells with single molecule precision.Open biology · 2012Review
- The seed nuclear proteome.Frontiers in plant science · 2012Article
- Emerging mechanisms of mRNP remodeling regulation.Wiley interdisciplinary reviews. RNAReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The nuclear pore complex (NPC) has long been viewed as a point-like entry and exit channel between the nucleus and the cytoplasm. New data support a different view whereby the complex displays distinct spatial dynamics of variable duration ranging from milliseconds to events spanning the entire cell cycle. Discrete interaction sites outside the central channel become apparent, and transport regulation at these sites seems to be of greater importance than currently thought. Nuclear pore components are highly active outside the NPC or impact the fate of cargo transport away from the nuclear pore. The NPC is a highly dynamic, crowded environment-constantly loaded with cargo while providing selectivity based on unfolded proteins. Taken together, this comprises a new paradigm in how we view import/export dynamics and emphasizes the multiscale nature of NPC-mediated cellular transport.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.