Evidence map›Paper›PMID 22196835›Full record

Trial reportJournal of cardiac failure2012

Effect of a medication-taking behavior feedback theory-based intervention on outcomes in patients with heart failure.

Jia-Rong Wu, Donna J Corley, Terry A Lennie, Debra K Moser

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cardiac failure, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Improving Treatment Adherence in Heart Failure.Deutsches Arzteblatt international · 2016
    Pooled it
  3. Pooled it
  4. Technology-mediated interventions for enhancing medication adherence.Journal of the American Medical Informatics Association : JAMIA · 2015
    Pooled it
  5. Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014
    Pooled it
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  11. Review
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  13. Article
  14. Interventions for increasing medication adherence in heart failure patients: A narrative review.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2024
    Review
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jia-Rong WuSchool of Nursing, University of North Carolina, Chapel Hill, North Carolina 27599-7460, USA. jiarongw@email.unc.edu
Donna J Corley
Terry A Lennie
Debra K Moser

Funding

Self-Management Pilot/Feasibility and Biobehavioral Outcomes CoreP20NR010679 · NINR · UNIVERSITY OF KENTUCKY · PI HALL, LYNNE ANDERSON · 2007 to 2011
$1.2M
NINR NIH HHS 1P20NR010679NINR NIH HHS P20 NR010679
6 · The paper itself

Abstract

backgroundMedication nonadherence contributes to hospitalization and mortality, yet there have been few interventions tested that improve adherence and reduce hospitalization and mortality in heart failure (HF). Our objective was to determine whether an education intervention improved medication adherence and cardiac event-free survival. METHODS AND

resultsA randomized controlled trial was conducted on 82 HF patients. The intervention was based on the theory of planned behavior (TPB) and included feedback of medication-taking behavior using the Medication Event Monitoring System (MEMS). Patients were assigned to one of three groups: 1) theory-based education plus MEMS feedback; 2) theory-based education only; or 3) usual care (control). Cardiac events were collected for 9 months. Patients in both intervention groups were more adherent over follow-up compared with the control group. In Cox regression, patients in either intervention group had a longer event-free survival compared with those in the control group before and after controlling age, marital status, financial status, ejection fraction, New York Heart Association functional class, angiotensin-converting enzyme inhibitor use, and presence or absence of a significant other during the intervention (P < .05).

conclusionsUse of an intervention based on the TPB improves medication adherence and outcomes in patients with HF and therefore offers promise as a clinically applicable intervention to help patients with HF to adhere to their prescribed regimen.

Indexed as

Behavior TherapyMedication AdherenceAngiotensin-Converting Enzyme InhibitorsFemaleHeart FailureHumansKentuckyMaleMiddle AgedProportional Hazards ModelsQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesSurvival AnalysisTreatment OutcomeAngiotensin-Converting Enzyme Inhibitors

Identifiers

PMID22196835
PMCPMC3246219

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.