Evidence map›Paper›PMID 22196287›Full record

ReviewLymphatic research and biology2011

Head and neck lymphatic tumors and bony abnormalities: a clinical and molecular review.

Karthik Balakrishnan, Mark Majesky, Jonathan A Perkins

Abstract readReview
In one paragraph

Review in Lymphatic research and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karthik BalakrishnanUniversity of Washington, Department of Otolaryngology/Head and Neck Surgery, Seattle, WA, USA.
Mark Majesky
Jonathan A Perkins

Funding

INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
Hedgehog Signaling in the AdventitiaR01HL093594 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAJESKY, MARK W. · 2009 to 2012
$1.8M
NCRR NIH HHS UL1 RR025014NHLBI NIH HHS R01 HL093594
6 · The paper itself

Abstract

Lymphatic malformations and lymphatic-derived tumors commonly involve the head and neck, where they may be associated with bony abnormalities and other systemic symptoms. The reasons for the association between these disorders and local skeletal changes are largely unknown, but such changes may cause significant disease-related morbidity. Ongoing work in molecular and developmental biology is beginning to uncover potential reasons for the bony abnormalities found in head and neck lymphatic disease; this article summarizes current knowledge on possible mechanisms underlying this association.

Indexed as

Bone and BonesBone DiseasesEndothelial CellsExtracellular MatrixHead and Neck NeoplasmsHumansNeoplasm, Lymphatic TissueRadiographySignal Transduction

Identifiers

PMID22196287
PMCPMC3391938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.