ReviewCritical reviews in biomedical engineering2011
Nitric oxide signaling in the microcirculation.
Review in Critical reviews in biomedical engineering, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Cellular nitric oxide synthesis is affected by disorders in the interdependentJournal of biological physics · 2023Article
- Transport of nitrite from large arteries modulates regional blood flow during stress and exercise.Frontiers in cardiovascular medicine · 2023Article
- Review
- The Aging Vasculature: Glucose Tolerance, Hypoglycemia and the Role of the Serum Response Factor.Journal of cardiovascular development and disease · 2021Review
- Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study.Biomedical optics express · 2020Article
- Signaling interplay between primary cilia and nitric oxide: A mini review.Nitric oxide : biology and chemistry · 2018Review
- The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats.Redox biology · 2018Article
- Nitric oxide release by deoxymyoglobin nitrite reduction during cardiac ischemia: A mathematical model.Microvascular research · 2017Article
- Can endothelial hemoglobin-α regulate nitric oxide vasodilatory signaling?American journal of physiology. Heart and circulatory physiology · 2017Article
- Nitrite-Mediated Hypoxic Vasodilation Predicted from Mathematical Modeling and Quantified fromFrontiers in physiology · 2017Article
- A mathematical model for the role of NNitric oxide : biology and chemistry · 2016Article
- Oxidative-Nitrosative Stress and Myocardial Dysfunctions in Sepsis: Evidence from the Literature and Postmortem Observations.Mediators of inflammation · 2016Review
- Compartmentalized nitric oxide signaling in the resistance vasculature.Nitric oxide : biology and chemistry · 2015Review
- Nitric oxide content and apoptosis rate in steroid-induced avascular necrosis of the femoral head.Experimental and therapeutic medicine · 2015Article
- Commentaries on viewpoint: A paradigm shift for local blood flow regulation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- Real-time RT-PCR Ct values for blood GAPDH correlate with measures of vascular endothelial function in humans.Clinical and translational science · 2013Article
- Mathematical and computational models of oxidative and nitrosative stress.Critical reviews in biomedical engineering · 2011Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Several apparent paradoxes are evident when one compares mathematical predictions from models of nitric oxide (NO) diffusion and convection in vasculature structures with experimental measurements of NO (or related metabolites) in animal and human studies. Values for NO predicted from mathematical models are generally much lower than in vivo NO values reported in the literature for experiments, specifically with NO microelectrodes positioned at perivascular locations next to different sizes of blood vessels in the microcirculation and NO electrodes inserted into a wide range of tissues supplied by the microcirculation of each specific organ system under investigation. There continues to be uncertainty about the roles of NO scavenging by hemoglobin versus a storage function that may conserve NO, and other signaling targets for NO need to be considered. This review describes model predictions and relevant experimental data with respect to several signaling pathways in the microcirculation that involve NO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.