Evidence map›Paper›PMID 22195990›Full record

ArticleRedox report : communications in free radical research2011

Oxidative stress and antioxidant defenses in pregnant women.

Claudio A M Leal, Maria R C Schetinger, Daniela B R Leal, Vera M Morsch, Aleksandro Schafer da Silva, João F P Rezer, André Valle de Bairros, Jeandre Augusto Dos Santos Jaques

Open access · bronzeAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Human Health Effects of Oral Exposure to Chromium: A Systematic Review of the Epidemiological Evidence.International journal of environmental research and public health · 2024
    Pooled it
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  14. Review
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  16. Oxidative Stress in Maternal Blood and Placenta From Mild Diabetic Rats.Reproductive sciences (Thousand Oaks, Calif.) · 2014
    Article
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  18. Eupomatenoid-5 Isolated from Leaves of Piper regnellii Induces Apoptosis in Leishmania amazonensis.Evidence-based complementary and alternative medicine : eCAM · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Claudio A M LealDepartamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. camleal@terra.com.br
Maria R C Schetinger
Daniela B R Leal
Vera M Morsch
Aleksandro Schafer da Silva
João F P Rezer
André Valle de Bairros
Jeandre Augusto Dos Santos Jaques
Universidade Federal de Santa Maria · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOxidative stress (OS) is defined as an imbalance in the production of reactive oxygen species and the capacity of antioxidant defenses. The objective of this work was to investigate OS and antioxidant capacity in pregnant women.

methodsParameters of the oxidative status and antioxidant capacity in serum and whole blood were evaluated in thirty-nine women with normal pregnancy.

resultsThe assessment of antioxidants indicated an increase in superoxide dismutase and catalase activities (P<0.05 and P<0.01) and a decrease in ascorbic acid levels and the total content of sulfhydryl (P<0.05 and P<0.001). Additionally, when the pro-oxidant system was investigated we found an increase (P<0.01) in malondialdehyde and no significant change (P>0.05) in protein carbonylation. DISCUSSION: This study demonstrates that there is a change in the pro-oxidant and antioxidant defenses associated with body and circulation changes that are inherent to the pregnancy process.

Indexed as

Oxidative StressAdultAntioxidantsAscorbic AcidCatalaseFemaleHumansLipid PeroxidationMalondialdehydeMiddle AgedOxidation-ReductionPregnancyProtein CarbonylationReactive Oxygen SpeciesSulfhydryl CompoundsSuperoxide DismutaseAntioxidantsAscorbic AcidCatalaseMalondialdehydeReactive Oxygen SpeciesSulfhydryl CompoundsSuperoxide Dismutase

Identifiers

PMID22195990
PMCPMC6837714
OpenAlexW2074861786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.