Evidence map›Paper›PMID 22195738›Full record

ArticleImmunity2011

T cell Myc-tabolism.

Jeffrey C Rathmell

Abstract readComment
In one paragraph

Article in Immunity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Glutaminolysis is a Potential Therapeutic Target for Kidney Diseases.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Epstein-Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Jeffrey C RathmellDepartment of Pharmacology and Cancer Biology, Department of Immunology, Sarah W. Stedman Nutrition and Metabolism Center, Duke University, Durham, NC 27710, USA. jeff.rathmell@duke.edu

Funding

T cell metabolism as a determinant of differentiation in allergic asthmaR01HL108006 · NHLBI · VANDERBILT UNIVERSITY · PI RATHMELL, JEFFREY C. · 2011 to 2014
$1.5M
NHLBI NIH HHS R01 HL108006
6 · The paper itself

Abstract

T cell activation leads to a dramatic demand for energy and biosynthetic precursors that is met by increased glucose and glutamine metabolism. In this issue of Immunity, Wang et al. (2011) show that Myc is essential in T cell metabolic reprogramming.

Identifiers

PMID22195738
PMCPMC3267318

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.