ArticleStroke research and treatment2011
A Parallel Thrombolysis Protocol with Nurse Practitioners As Coordinators Minimized Door-to-Needle Time for Acute Ischemic Stroke.
Article in Stroke research and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effect of implementing care protocols on acute ischemic stroke outcomes: a systematic review.Arquivos de neuro-psiquiatria · 2023Pooled it
- Reducing care time after implementing protocols for acute ischemic stroke: a systematic review.Arquivos de neuro-psiquiatria · 2022Pooled it
- Factors delaying intravenous thrombolytic therapy in acute ischaemic stroke: a systematic review of the literature.Journal of neurology · 2021Pooled it
- Effectiveness of interventions to improve rates of intravenous thrombolysis using behaviour change wheel functions: a systematic review and meta-analysis.Implementation science : IS · 2020Pooled it
- Pooled it
- Nurse Practitioner Contribution to Shortening the Time from Angiography Suite Entry to Puncture in Mechanical Thrombectomy for Acute Ischemic Stroke.Journal of neuroendovascular therapy · 2026Article
- Teleneurocritical Care for Patients with Large Vessel Occlusive Ischemic Stroke Treated by Thrombectomy.Neurocritical care · 2023Article
- Temporal trends in reperfusion therapy for patients with acute ischemic stroke.Journal of the American College of Emergency Physicians open · 2022Article
- Clinical significance of stroke nurse in patients with acute ischemic stroke receiving intravenous thrombolysis.BMC neurology · 2021Article
- Meeting the evolving demands of neurointervention: Implementation and utilization of nurse practitioners.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019Article
- 24/7 Neurocritical Care Nurse Practitioner Coverage Reduced Door-to-Needle Time in Stroke Patients Treated with Tissue Plasminogen Activator.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2016Article
- Process improvement to enhance existing stroke team activity toward more timely thrombolytic treatment.Journal of clinical neurology (Seoul, Korea) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction. Quick thrombolysis after stroke improved clinical outcomes. The study objective was to shorten door-to-needle time for thrombolysis. Methods. After identifying the sources of in-hospital delays, we developed a protocol with a parallel algorithm and recruited nurse practitioners into the acute stroke team. We applied the new protocol on stroke patients from October 2009 to September 2010. Patients from the previous two years were used for comparison. Results. For ischemic stroke patients within 3 hours of onset, the median time from arrival to computed tomography scanning was reduced from 29 to 20 minutes (P < 0.001) and the median time from arrival to neurology evaluation decreased from 61 to 43 minutes (P < 0.001). For those patients who received thrombolysis, the median door-to-needle time was shortened from 68.5 to 58 minutes (P < 0.05). Conclusions. The parallel thrombolysis protocol successfully improved the median door-to-needle time to below the guideline-recommended 60 minutes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.