Evidence map›Paper›PMID 22195242›Full record

ArticleGut and liver2011

Treatment for Eradication of Helicobacter pylori Infection among Chronic Hepatitis C Patients.

Norihiro Furusyo, Ahmed H Walaa, Kunimitsu Eiraku, Kazuhiro Toyoda, Eiichi Ogawa, Hiroaki Ikezaki, Takeshi Ihara, Takeo Hayashi, Mosaburo Kainuma, Masayuki Murata and 1 more

Abstract read
In one paragraph

Article in Gut and liver, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. TargetingJournal of clinical biochemistry and nutrition · 2025
    Article
  6. Observational
  7. CagA-positiveFrontiers in microbiology · 2024
    Article
  8. Article
  9. Review
  10. Serum pepsinogen and Helicobacter pylori infection--a Japanese population study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Norihiro FurusyoDepartment of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan.
Ahmed H Walaa
Kunimitsu Eiraku
Kazuhiro Toyoda
Eiichi Ogawa
Hiroaki Ikezaki
Takeshi Ihara
Takeo Hayashi
Mosaburo Kainuma
Masayuki Murata
Jun Hayashi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsHelicobacter pylori infection causes gastritis, peptic ulcers and gastric malignancies, and its eradication has been advocated by many groups. We determined the H. pylori carrier status and eradication rates of patients with chronic hepatitis C virus (HCV) infection.

methodsIn total, 76 chronically HCV-infected patients were enrolled for comparison with 228 HCV-noninfected, age- and sex-matched controls. H. pylori infection was confirmed by H. pylori antibody and urea breath testing.

resultsThe H. pylori infection rate was significantly higher for HCV-infected patients (67 of 76, 88.2%) than for HCV-noninfected controls (158 of 228, 69.3%). Endoscopic findings showed that the rates of gastric ulcers and gastritis were significantly higher for the 67 HCV-infected patients with H. pylori infection (34.3% and 77.6%) than for the 158 HCV-noninfected controls with H. pylori infection (15.2% and 57.6%). Treatment to eradicate H. pylori had a significantly higher success rate for HCV-infected patients (61 of 67, 91.0%) than for HCV-noninfected controls (115 of 158, 72.8%).

conclusionsThe markedly high H. pylori eradication rate observed in this study shows that eradication of H. pylori holds promise for the improvement of the long-term health condition of patients with chronic HCV infection.

Indexed as

Chronic hepatitis CHelicobacter pylori

Identifiers

PMID22195242
PMCPMC3240787

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.