Evidence map›Paper›PMID 22195216›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2011

Graph-based methods for discovery browsing with semantic predications.

Bartłomiej Wilkowski, Marcelo Fiszman, Christopher M Miller, Dimitar Hristovski, Sivaram Arabandi, Graciela Rosemblat, Thomas C Rindflesch

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Drug repurposing for COVID-19 via knowledge graph completion.Journal of biomedical informatics · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. A Literature Based Discovery Visualization System with Hierarchical Clustering and Linking Set Associations.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bartłomiej WilkowskiTechnical University of Denmark, DTU Informatics, Kongens Lyngby, DK-2800, Denmark.
Marcelo Fiszman
Christopher M Miller
Dimitar Hristovski
Sivaram Arabandi
Graciela Rosemblat
Thomas C Rindflesch

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

We present an extension to literature-based discovery that goes beyond making discoveries to a principled way of navigating through selected aspects of some biomedical domain. The method is a type of "discovery browsing" that guides the user through the research literature on a specified phenomenon. Poorly understood relationships may be explored through novel points of view, and potentially interesting relationships need not be known ahead of time. In a process of "cooperative reciprocity" the user iteratively focuses system output, thus controlling the large number of relationships often generated in literature-based discovery systems. The underlying technology exploits SemRep semantic predications represented as a graph of interconnected nodes (predication arguments) and edges (predicates). The system suggests paths in this graph, which represent chains of relationships. The methodology is illustrated with depressive disorder and focuses on the interaction of inflammation, circadian phenomena, and the neurotransmitter norepinephrine. Insight provided may contribute to enhanced understanding of the pathophysiology, treatment, and prevention of this disorder.

Indexed as

MEDLINENatural Language ProcessingDepressive DisorderHumansInformation Storage and RetrievalSemanticsUnified Medical Language System

Identifiers

PMID22195216
PMCPMC3243228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.