Evidence map›Paper›PMID 22195081›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2011

Medical record and imaging evaluation to identify arterial tortuosity phenotype in populations at risk for intracranial aneurysms.

Karl T Diedrich, John A Roberts, Richard H Schmidt, Lisa A Cannon Albright, Anji T Yetman, Dennis L Parker

Open access · greenAbstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Arterial tortuosity in genetic arteriopathies.Current opinion in cardiology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karl T DiedrichUtah Center for Advanced Imaging Research, Department of Radiology, University of Utah, 729 Arapeen Drive, Salt Lake City, UT 84108, USA. Karl.Diedrich@utah.edu
John A Roberts
Richard H Schmidt
Lisa A Cannon Albright
Anji T Yetman
Dennis L Parker
University of Utah · US

Funding

UNIVERSITY OF UTAH MEDICAL INFORMATICS TRAININGT15LM007124 · NLM · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Karen Louise Eilbeck · 1997 to 2026
$22.0M
HIGH RESOLUTION MR ANGIOGRAPHYR01HL048223 · NHLBI · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 1993 to 2007
$2.0M
MAPPING INTRACRANIAL ANEURYSM SUSCEPTIBILITY LOCIR01NS037737 · NINDS · UNIVERSITY OF UTAH · PI CANNON ALBRIGHT, LISA A. · 1998 to 2001
$778k
NHLBI NIH HHS R01 HL048223NHLBI NIH HHS R01-HL-48223NINDS NIH HHS R01-NS-37737NLM NIH HHS T15 LM007124NLM NIH HHS T15LM007124
6 · The paper itself

Abstract

High arterial tortuosity may signify early arterial pathology which may precede development of intracranial aneurysms. We measured arterial tortuosity of intracranial vessels and reviewed the medical records of three groups of patients: with intracranial aneurysms, without aneurysms but at increased clinical risk, and controls without aneurysms or associated risk factors. There was significant but inconsistent evidence of increased arterial tortuosity in aneurysm cases and high-risk cases across different arteries. Medical records review identified that a subset of aneurysm cases carried a diagnosis of Loeys-Dietz syndrome that is often misdiagnosed as Marfan syndrome. We found increased arterial tortuosity in the Loeys-Dietz syndrome cases. A combination of medical record screening for Marfan syndrome or Loeys-Dietz symptoms such as aneurysms and evaluation of arterial tortuosity by a curve of scores from medical images may identify previously undiagnosed cases of Loeys-Dietz syndrome.

Indexed as

Basilar ArteryCerebral ArteriesDiagnostic ImagingElectronic Health RecordsHumansIntracranial AneurysmLoeys-Dietz SyndromeMagnetic Resonance AngiographyPhenotypeAneurysmLoeys-DietzMRAtortuosity

Identifiers

PMID22195081
PMCPMC3243263
OpenAlexW56079957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.