ArticlePloS one2011
Regulation of apoptotic pathways by Stylophora pistillata (Anthozoa, Pocilloporidae) to survive thermal stress and bleaching.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 73 citations in OpenAlex.
- A multi-molecular biomarker assessment of thermal preconditioning in two scleractinian coral species.Scientific reports · 2025Article
- Genomes of the Caribbean reef-building corals Colpophyllia natans, Dendrogyra cylindrus, and Siderastrea siderea.G3 (Bethesda, Md.) · 2025Article
- Integrated metagenomic and metaproteomic analyses reveal bacterial micro-ecological mechanisms in coral bleaching.mSystems · 2023Article
- The history, biological relevance, and potential applications for polyp bailout in corals.Ecology and evolution · 2021Review
- Eighteen Coral Genomes Reveal the Evolutionary Origin of Acropora Strategies to Accommodate Environmental Changes.Molecular biology and evolution · 2021Article
- Apoptosis in gonadal somatic cells of scleractinian corals: implications of structural adjustments for gamete production and release.Proceedings. Biological sciences · 2020Article
- Resilience of the prokaryotic microbial community of Acropora digitifera to elevated temperature.MicrobiologyOpen · 2017Article
- The regulation of thermal stress induced apoptosis in corals reveals high similarities in gene expression and function to higher animals.Scientific reports · 2016Article
- Dimethylsulfoniopropionate, superoxide dismutase and glutathione as stress response indicators in three corals under short-term hyposalinity stress.Proceedings. Biological sciences · 2016Article
- Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora.BMC genomics · 2016Article
- Article
- Relative Contributions of Various Cellular Mechanisms to Loss of Algae during Cnidarian Bleaching.PloS one · 2016Article
- Breakdown of coral colonial form under reduced pH conditions is initiated in polyps and mediated through apoptosis.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Toxicological effects of the sunscreen UV filter, benzophenone-2, on planulae and in vitro cells of the coral, Stylophora pistillata.Ecotoxicology (London, England) · 2014Article
- Extensive differences in gene expression between symbiotic and aposymbiotic cnidarians.G3 (Bethesda, Md.) · 2014Article
- Seasonal mesophotic coral bleaching of Stylophora pistillata in the Northern Red Sea.PloS one · 2014Article
- Article
- Increased cell proliferation and mucocyte density in the sea anemone Aiptasia pallida recovering from bleaching.PloS one · 2013Article
- Severe impact and subsequent recovery of a coral assemblage following the 1997-8 El Niño event: a 17-year study from Bahia, Brazil.PloS one · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elevated seawater temperatures are associated with coral bleaching events and related mortality. Nevertheless, some coral species are able to survive bleaching and recover. The apoptotic responses associated to this ability were studied over 3 years in the coral Stylophora pistillata from the Gulf of Eilat subjected to long term thermal stress. These include caspase activity and the expression profiles of the S. pistillata caspase and Bcl-2 genes (StyCasp and StyBcl-2-like) cloned in this study. In corals exposed to thermal stress (32 or 34°C), caspase activity and the expression levels of the StyBcl-2-like gene increased over time (6-48 h) and declined to basal levels within 72 h of thermal stress. Distinct transcript levels were obtained for the StyCasp gene, with stimulated expression from 6 to 48 h of 34°C thermal stress, coinciding with the onset of bleaching. Increased cell death was detected in situ only between 6 to 48 h of stress and was limited to the gastroderm. The bleached corals survived up to one month at 32°C, and recovered back symbionts when placed at 24°C. These results point to a two-stage response in corals that withstand thermal stress: (i) the onset of apoptosis, accompanied by rapid activation of anti-oxidant/anti-apoptotic mediators that block the progression of apoptosis to other cells and (ii) acclimatization of the coral to the chronic thermal stress alongside the completion of symbiosis breakdown. Accordingly, the coral's ability to rapidly curb apoptosis appears to be the most important trait affecting the coral's thermotolerance and survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.