Evidence map›Paper›PMID 22194722›Full record

ArticleFrontiers in pharmacology2011

Antioxidant Capacity and Polyphenolic Composition as Quality Indicators for Aqueous Infusions of Salvia officinalis L. (sage tea).

Stephan G Walch, Laura Ngaba Tinzoh, Benno F Zimmermann, Wolf Stühlinger, Dirk W Lachenmeier

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 91 citations in OpenAlex.

  1. Optimized Ultrasound-Assisted Extraction RevealsAntioxidants (Basel, Switzerland) · 2026
    Article
  2. An Ethnopharmacological Survey on Medicinally Important Plants of Genus Salvia.Combinatorial chemistry & high throughput screening · 2025
    Review
  3. Sage (Anatomy & cell biology · 2024
    Article
  4. Article
  5. Article
  6. Frontiers in pharmacology · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Antimicrobial and cytotoxic activity of extracts fromPhysiology and molecular biology of plants : an international journal of functional plant biology · 2019
    Article
  18. Molecules (Basel, Switzerland) · 2018
    Article
  19. Quality Variation of Goji (Fruits ofFrontiers in pharmacology · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stephan G WalchDepartment for Public Health and Health Technology Assessment, University for Health Sciences, Medical Informatics and Technology Hall in Tyrol, Austria.
Laura Ngaba Tinzoh
Benno F Zimmermann
Wolf Stühlinger
Dirk W Lachenmeier
Austrian Institute for Health Technology Assessment GmbH · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sage (Salvia officinalis L.) is used as an herbal medicinal product, with the most typical form of application as infusion with boiling water (sage tea). The well-established traditional uses include symptomatic treatment of mild dyspeptic complaints, the treatment of inflammations in the mouth and the throat, and relief of excessive sweating and relief of minor skin inflammations. In this study, sage teas prepared from commercially available products were chemically analyzed for polyphenolic content using liquid chromatography, for antioxidant potential using the oxygen radical absorbance capacity method, and for the Folin-Ciocalteu (FC) index. The sage teas showed a high variation for all parameters studied (up to 20-fold differences for rosmarinic acid). Univariate and multivariate analyses showed that the antioxidant potential, which varied between 0.4 and 1.8 mmol trolox equivalents/100 mL, was highly dependent on rosmarinic acid and its derivatives. The FC index also showed a high correlation to these polyphenols, and could therefore be used as a screening parameter for sage tea quality. The considerable differences in polyphenolic composition and antioxidant capacity between the brands lead to a demand for quality standardization, especially if these sage teas are to be used for therapeutic purposes. Further research also appears to be necessary to characterize the dose-benefit relationship, as sage may also contain a constituent (thujone) with potentially adverse effects.

Indexed as

antioxidant capacityORACpolyphenolsSalvia officinalis L.tea infusion

Identifiers

PMID22194722
PMCPMC3242359
OpenAlexW2055568709

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.