Evidence map›Paper›PMID 22194386›Full record

ArticleAJNR. American journal of neuroradiology2012

Outcomes of endovascular treatments of aneurysms: observer variability and implications for interpreting case series and planning randomized trials.

É Tollard, T E Darsaut, F Bing, F Guilbert, G Gevry, J Raymond

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  5. Embolization with larger-caliber coils can increase packing density: Evidence from the pilot phase of a randomized trial.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
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  6. Endovascular treatment of aneurysms and platinum coil caliber: Study protocol of a randomized, controlled trial.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2016
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  20. Point-TAR: a useful index to follow-up coiled intracranial aneurysms?AJNR. American journal of neuroradiology · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

É TollardDepartment of Neuroradiology, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.
T E Darsaut
F Bing
F Guilbert
G Gevry
J Raymond

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAngiographic results are commonly used as a surrogate marker of success of coiling of intracranial aneurysms. Inter- and intraobserver agreement in judging angiographic results remain poorly characterized. Our goal was to offer such an evaluation of a grading scale commonly used to evaluate results of endovascular treatment of aneurysms. MATERIALS AND

methodsA portfolio of 90 angiographic images from 45 patients selected from the core lab data base of a randomized trial was sent to 12 observers on 2 occasions more than 3 months apart. The variability of a 3-value grading scale used to score angiographic results and of a final judgment regarding the presence of a recurrence was studied using κ statistics.

resultsTen participants responded once and 6 responded twice. Agreement was poor to moderate (κ = 0.28-0.5) for senior and junior observers judging angiographic results immediately or 12-18 months after treatment. Agreement reached a reassuring "substantial" (κ = 0.62) level, with a dichotomous presence-absence of a major recurrence, and intraobserver agreement was better in experienced core lab assessors.

conclusionsThere is an important variability in the assessment of angiographic outcomes of endovascular treatments, rendering comparisons between publications risky, if not invalid. A simple dichotomous judgment can be used as a surrogate outcome in randomized trials designed to assess the value of new endovascular devices.

Indexed as

Cerebral AngiographyAdultAgedEndovascular ProceduresHumansIntracranial AneurysmMaleMechanical ThrombolysisMiddle AgedObserver VariationReproducibility of ResultsSensitivity and SpecificityTreatment Outcome

Identifiers

PMID22194386
PMCPMC8050430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.