Evidence map›Paper›PMID 22194365›Full record

ArticleAJNR. American journal of neuroradiology2012

Performance of semiautomatic assessment of carotid artery stenosis on CT angiography: clarification of differences with manual assessment.

H A Marquering, P J Nederkoorn, L Smagge, H A Gratama van Andel, R van den Berg, C B Majoie

Abstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

H A MarqueringDepartment of Radiology, Academic Medical Center, Amsterdam, The Netherlands. H.A.Marquering@amc.uva.nl
P J Nederkoorn
L Smagge
H A Gratama van Andel
R van den Berg
C B Majoie

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSemiautomated methods for ICA stenosis measurements have the potential to reduce interobserver variability and to speed up its analysis. In this study, we estimate the precision and accuracy of a semiautomated measurement for carotid artery stenosis degree and identify and explain differences compared with the manual method. MATERIALS AND

methodsIn this retrospective study involving 90 patients, 2 observers determined the stenosis degree twice, with both the semiautomated and the manual method. Intra- and interobserver correlations were calculated for both methods. The accuracy was estimated by comparing average semiautomated with manual measurements. The semiautomated stenosis calculations were performed using either the minimal or maximal intersection at the reference site. Individual cases with large differences in measurement were retrospectively inspected by 3 observers.

resultsIntra- (R = 0.93, 0.96) and interobserver (R = 0.98) correlations for the semiautomated method were excellent and exceeded the manual performance correlations (R = 0.87, 0.86). The semiautomated measurements correlated well with the manual measurements (R = 0.87), with high specificity of 96% and lower sensitivity of 63%. Large differences were caused by misinterpretations of the semiautomated method associated with calcified plaques, resulting in overestimations of the minimal diameter, underestimation of stenosis degree, and incorrect centerlines. The effect of using the minimal diameter at the reference position resulted in a small, but significant, underestimation of the stenosis degree by the semiautomated method.

conclusionsThe semiautomated method showed an excellent reproducibility and good correlation with manual measurements with a high specificity and lower sensitivity for detecting a significant stenosis. Erroneous semiautomatic stenosis measurements were associated with the presence of calcium.

Indexed as

AlgorithmsAdultAgedAged, 80 and overCarotid StenosisCerebral AngiographyFemaleHumansMaleMiddle AgedObserver VariationPattern Recognition, AutomatedRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID22194365
PMCPMC8050455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.