ArticleComparative biochemistry and physiology. Part A, Molecular & integrative physiology2012
Expression of aquaporin 3 in gills of the Atlantic killifish (Fundulus heteroclitus): Effects of seawater acclimation.
Article in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 38 citations in OpenAlex.
- Expression of genes encoding non-specific immunity, anti-oxidative status and aquaporins in β-glucan-fed golden mahseer (Fish and shellfish immunology reports · 2023Article
- Is aquaporin-3 involved in water-permeability changes in the killifish during hypoxia and normoxic recovery, in freshwater or seawater?Journal of experimental zoology. Part A, Ecological and integrative physiology · 2020Article
- The osmorespiratory compromise in the euryhaline killifish: water regulation during hypoxia.The Journal of experimental biology · 2019Article
- Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Cells · 2019Article
- The effects of transfer from steady-state to tidally-changing salinities on plasma and branchial osmoregulatory variables in adult Mozambique tilapia.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2019Article
- Does Body Shape inFrontiers in physiology · 2019Article
- Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish.Environmental science & technology · 2018Article
- RNA-Seq analysis of salinity stress-responsive transcriptome in the liver of spotted sea bass (Lateolabrax maculatus).PloS one · 2017Article
- Trade-offs between salinity preference and antipredator behaviour in the euryhaline sailfin molly Poecilia latipinna.Journal of fish biology · 2016Article
- Molecular Characterization of Aquaporin 1 and Aquaporin 3 from the Gills of the African Lungfish,Frontiers in physiology · 2016Article
- Prolactin 177, prolactin 188, and extracellular osmolality independently regulate the gene expression of ion transport effectors in gill of Mozambique tilapia.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Article
- A novel variant of aquaporin 3 is expressed in killifish (Fundulus heteroclitus) intestine.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- A novel aquaporin 3 in killifish (Fundulus heteroclitus) is not an arsenic channel.Toxicological sciences : an official journal of the Society of Toxicology · 2012Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Estuarine fish, such as the Atlantic killifish (Fundulus heteroclitus), are constantly and rapidly exposed to changes in salinity. Although ion transport in killifish gills during acclimation to increased salinity has been studied extensively, no studies have examined the role of aquaglyceroporin 3 (AQP3), a water, glycerol, urea, and ammonia transporter, during acclimation to increased salinity in this sentinel environmental model organism. The goal of this study was to test the hypothesis that transfer from freshwater to seawater decreases AQP3 gene and protein expression in the gill of killifish. Transfer from freshwater to seawater decreased AQP3 mRNA in the gill after 1 day, but had no effect on total gill AQP3 protein abundance as determined by western blot. Quantitative confocal immunocytochemistry confirmed western blot studies that transfer from freshwater to seawater did not change total AQP3 abundance in the gill; however, immunocytochemistry revealed that the amount of AQP3 in pillar cells of secondary lamellae decreased in seawater fish, whereas the amount of AQP3 in mitochondrion rich cells (MRC) in primary filaments of the gill increased in seawater fish. This response of AQP3 expression is unique to killifish compared to other teleosts. Although the role of AQP3 in the gill of killifish has not been completely elucidated, these results suggest that AQP3 may play an important role in the ability of killifish to acclimate to increased salinity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.