Evidence map›Paper›PMID 22193162›Full record

ReviewNature cell biology2011

Shaping development with ESCRTs.

Tor Erik Rusten, Thomas Vaccari, Harald Stenmark

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Function of Ubiquitination in T-Cell Development.Advances in experimental medicine and biology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Regulatory mechanisms of cytoneme-based morphogen transport.Cellular and molecular life sciences : CMLS · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Antibody-Drug Conjugates: The New Frontier of Chemotherapy.International journal of molecular sciences · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. A rheostat tuning thymic selection.Nature immunology · 2017
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tor Erik RustenCentre for Cancer Biomedicine, Oslo University Hospital, Montebello, 0310 Oslo, Norway.
Thomas Vaccari
Harald Stenmark
FIRC Institute of Molecular Oncology · ITOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Originally identified for their involvement in endosomal sorting and multivesicular endosome (MVE) biogenesis, components of the endosomal sorting complex required for transport (ESCRT) are now known to control additional cellular functions such as receptor signalling, cytokinesis, autophagy, polarity, migration, miRNA activity and mRNA transport. The diverse cell biological functions of ESCRT proteins are translated into a pleiotropic set of developmental trajectories that reflect the wide repertoire of these evolutionarily conserved proteins.

Indexed as

AnimalsEndosomal Sorting Complexes Required for TransportHumansMultivesicular BodiesProtein TransportEndosomal Sorting Complexes Required for Transport

Identifiers

PMID22193162
OpenAlexW2015614032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.