Evidence map›Paper›PMID 22193158›Full record

ReviewNature cell biology2011

Lessons from yeast for clathrin-mediated endocytosis.

Douglas R Boettner, Richard J Chi, Sandra K Lemmon

Abstract readReview
In one paragraph

Review in Nature cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
  2. Endocytosis and trans-Golgi Network in Yeast.Sub-cellular biochemistry · 2026
    Review
  3. Article
  4. A role for cross-linking proteins in actin filament network organization and force generation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. TheJournal of cell science · 2019
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Douglas R BoettnerDepartment of Molecular and Cellular Pharmacology (R-189), Miller School of Medicine, University of Miami, Miami, Florida 33101, USA.
Richard J Chi
Sandra K Lemmon

Funding

SUPPRESSORS OF CLATHRIN DEFICIENCY IN YEASTR01GM055796 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LEMMON, SANDRA K. · 1998 to 2015
$4.7M
TRAINING PROGRAMS IN CARDIOVASCULAR PHARMACOLOGYT32HL007188 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SZCZESNA-CORDARY, DANUTA · 1985 to 2011
$3.8M
Regulation of endoytosis by clathrin light chain.F32GM084677 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BOETTNER, DOUGLAS ROBB · 2008 to 2010
$149k
Phospho-regulation of Endocytosis by multifunctional PP1 targeting protein Scd5F32GM087900 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHI, RICHARD J · 2009 to 2010
$83k
NHLBI NIH HHS T32 HL007188NHLBI NIH HHS T32-HL07188NIGMS NIH HHS F32 GM084677NIGMS NIH HHS F32-GM084677NIGMS NIH HHS F32 GM087900NIGMS NIH HHS F32-GM087900NIGMS NIH HHS R01 GM055796NIGMS NIH HHS R01-GM055796
6 · The paper itself

Abstract

Clathrin-mediated endocytosis (CME) is the major pathway for internalization of membrane proteins from the cell surface. Half a century of studies have uncovered tremendous insights into how a clathrin-coated vesicle is formed. More recently, the advent of live-cell imaging has provided a dynamic view of this process. As CME is highly conserved from yeast to humans, budding yeast provides an evolutionary template for this process and has been a valuable system for dissecting the underlying molecular mechanisms. In this review we trace the formation of a clathrin-coated vesicle from initiation to uncoating, focusing on key findings from the yeast system.

Indexed as

AnimalsCell MembraneClathrin-Coated VesiclesHumansMembrane ProteinsYeastsMembrane Proteins

Identifiers

PMID22193158
PMCPMC5590828

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.