ArticleAnnals of intensive care2011
Community-acquired necrotizing pneumonia due to methicillin-sensitive Staphylococcus aureus secreting Panton-Valentine leukocidin: a review of case reports.
Article in Annals of intensive care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 55 citations in OpenAlex.
- Treatment of Methicillin-ResistantMedicines (Basel, Switzerland) · 2026Review
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- Neonatal presumed septic pulmonary embolism associated with a peripherally inserted central catheter: a case report.Frontiers in pediatrics · 2026Article
- Culture-Confirmed Severe Methicillin-SusceptibleInfection and drug resistance · 2026Article
- A Comprehensive Review of Pediatric Necrotizing Pneumonia.Children (Basel, Switzerland) · 2025Review
- Necrotizing Pneumonia as a Complication of Community-Acquired Pneumonia in Adults at a Tertiary Institution.Journal of clinical medicine · 2025Article
- Article
- Necrotizing pneumonia secondary to Influenza A (H1N1) coinfection with Staphylococcus aureus: A case report.IDCases · 2024Article
- A Study on the Epidemiological-Molecular Role ofAntibiotics (Basel, Switzerland) · 2023Article
- Tissue specificity drives protective immunity againstFrontiers in immunology · 2022Article
- Prognostic factors of severe community-acquired staphylococcal pneumonia in France.The European respiratory journal · 2021Article
- The First Report of a Methicillin-ResistantPathogens (Basel, Switzerland) · 2021Article
- Article
- Panton-Valentine Leukocidin-Secreting Staphylococcus aureus Pneumonia Complicating COVID-19.Emerging infectious diseases · 2020Article
- Phylogenetic and Molecular Profile ofMicroorganisms · 2019Article
- Empyema thoracis secondary to community-acquired Panton-Valentine leukocidin (PVL) methicillin-resistantBMJ case reports · 2019Article
- Association ofInfection and drug resistance · 2019Article
- Serious life-threatening multifocal infection in a child, caused by Panton-Valentine leucocidin-producingBMJ case reports · 2018Article
- Management of methicillin-resistantCurrent trends in microbiology · 2018Article
- Subscapular Abscess Caused by Panton-Valentine Leukocidin-PositiveCase reports in orthopedics · 2018Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCommunity-acquired necrotizing pneumonia caused by Panton-Valentine leukocidin (PVL)-secreting Staphylococcus aureus is a highly lethal infection that mainly affects healthy children and young adults. Both methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) may carry the PVL-phage, but the majority of publications relate to community-associated methicillin-resistant S. aureus (CA-MRSA) or mixed patient groups. This study focuses on necrotizing pneumonia due to methicillin-sensitive S. aureus strains, with the purpose to determine factors associated with outcome.
methodsWe report a patient with PVL secreting MSSA necrotizing pneumonia and performed a systematic review of similar case in the literature. We analyzed factors associated with outcome.
resultsA total of 32 patient descriptions were retained for analysis. Septic shock (p = 0.007), influenza-like prodrome (p = 0.02), and the absence of a previous skin and soft-tissue infection (p = 0.024) were associated with fatal outcome. In multivariate analysis, influenza-like prodrome (odds ratio (OR), 7.44; 95% confidence interval (CI), 1.24-44.76; p = 0.028) and absence of previous skin and soft-tissue infection (OR, 0.09; 95% CI, 0.01-0.86; p = 0.036) remained significant predictors of death.
conclusionsInfluenza-like prodrome may be predictive of adverse outcome in PVL-secreting MSSA necrotizing pneumonia. In contrast, previous skin and soft-tissue infection may be associated with improved prognosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.