Evidence map›Paper›PMID 22192274›Full record

ReviewCurrent opinion in cell biology2012

The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm.

Takeshi Shimi, Veronika Butin-Israeli, Robert D Goldman

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Diseases of the Nucleoskeleton.Comprehensive Physiology · 2016
    Review
  6. An unresolved LINC in the nuclear envelope.Cellular and molecular bioengineering · 2016
    Article
  7. Functional roles of HIV-1 Tat protein in the nucleus.Cellular and molecular life sciences : CMLS · 2016
    Review
  8. Article
  9. Role of lamin b1 in chromatin instability.Molecular and cellular biology · 2015
    Article
  10. Article
  11. Article
  12. Article
  13. Computational design of a red fluorophore ligase for site-specific protein labeling in living cells.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Condensins and 3D Organization of the Interphase Nucleus.Current genetic medicine reports · 2013
    Article
  19. Mechanical model of blebbing in nuclear lamin meshworks.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Takeshi ShimiDepartment of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Veronika Butin-Israeli
Robert D Goldman
Northwestern University · US

Funding

INTERMEDIATE FILAMENTS IN NORMAL AND TRANSFORMED CELLSR01CA031760 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GOLDMAN, ROBERT D · 1985 to 2013
$4.9M
NCI NIH HHS R01 CA031760
6 · The paper itself

Abstract

Recent studies of the nuclear envelope (NE) have emphasized its role in linking the nuclear and cytoplasmic compartments of mammalian cells. The inner face of the NE is bound to chromatin and this interaction is involved in regulating DNA replication and transcription. The outer face of the NE binds to different components of the cytoskeleton, and these interactions are involved in nuclear positioning. Many disease causing mutations in genes encoding NE proteins cause significant changes in nuclear architecture and cytoskeletal interactions with the NE. These mutations are also providing important new insights into nuclear-cytoplasmic interactions.

Indexed as

AnimalsCell NucleusCytoplasmCytoskeletonHumansNuclear EnvelopeNuclear ProteinsOrganelle ShapeNuclear Proteins

Identifiers

PMID22192274
PMCPMC3339630
OpenAlexW1969081908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.