Evidence map›Paper›PMID 22191677›Full record

ArticleGenetic testing and molecular biomarkers2012

Perceptions about genetic testing for the susceptibility to alcohol dependence and other multifactorial diseases.

Vanessa J Marshall, Nnenna Kalu, John Kwagyan, Carla Williams, Robert E Taylor, Denise M Scott

Abstract read
In one paragraph

Article in Genetic testing and molecular biomarkers, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vanessa J MarshallAlcohol Research Center, College of Medicine, Howard University, Washington, District of Columbia 20059, USA. vjmarshall@howard.edu
Nnenna Kalu
John Kwagyan
Carla Williams
Robert E Taylor
Denise M Scott
Howard University · US

Funding

UVDM01RR010284 · NCRR · HOWARD UNIVERSITY · PI TAYLOR, ROBERT E. · 1996 to 2010
$17.4M
IRPG4:NOVEL PHENOTYPES FOR GENETICS OF ALCOHOLISMR01AA012553 · NIAAA · HOWARD UNIVERSITY · PI TAYLOR, ROBERT E · 1999 to 2003
$2.9M
PRENATAL ALCOHOL--EFFECTS ON CENTRAL DOPAMINE RECEPTOR SUBTYPESU24AA011898 · NIAAA · HOWARD UNIVERSITY · PI TIZABI, YOUSEF · 1997 to 2002
$1.7M
NCRR NIH HHS M01-RR10284NIAAA NIH HHS AA-012553NIAAA NIH HHS AA-11898
6 · The paper itself

Abstract

backgroundBeliefs, attitudes, and preferences about the risk and benefits of genetic testing are important determinants of willingness to undergo testing.

aimsThe purpose of this study was to evaluate the perceived importance of genetic testing for alcohol dependence compared with other multifactorial diseases among African Americans.

methodsSurveys were conducted with 258 participants using the Genetic Psycho-Social Implications (GPSI) questionnaire to evaluate several areas of hypothetical genetic testing for alcohol dependence. Respondents were divided into two groups: those who perceived testing for alcohol dependence to be equally important as testing for cancer and those who did not. Using chi-square, the groups' responses were compared for nine GPSI items measuring beliefs about the severity of alcohol dependence, general benefits of genetic testing, and specific benefits of genetic testing for diabetes, hypertension, or a disease affecting a family member.

resultsNearly 86% of respondents believed that genetic testing for alcoholism was equally as important as testing for cancer. Those who reported parity of importance of alcohol dependence and cancer screening were more likely to believe that alcoholism is a deadly disease (p<0.001) and genetic testing influences health (p<0.001).

conclusionAfrican Americans reported favorable attitudes and beliefs in possible availability of susceptibility genetic testing for alcohol dependence. The perceived importance of testing for alcohol dependence was associated with beliefs about the severity of alcoholism and certain benefits of genetic testing in general.

Indexed as

Attitude to HealthGenetic Predisposition to DiseaseGenetic TestingAdolescentAdultAgedAged, 80 and overAlcoholismBlack or African AmericanFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNeoplasmsPerception

Identifiers

PMID22191677
PMCPMC3378024
OpenAlexW1964509632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.