Evidence map›Paper›PMID 22191092›Full record

ArticleAngewandte Chemie (International ed. in English)2011

Multivalent glycocluster design through directed evolution.

Iain S MacPherson, J Sebastian Temme, Sevan Habeshian, Krzysztof Felczak, Krzysztof Pankiewicz, Lizbeth Hedstrom, Isaac J Krauss

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. ACS central science · 2025
    Article
  2. Article
  3. Selection of antibody-binding covalent aptamers.Communications chemistry · 2024
    Article
  4. Large-Scale Synthesis of ManACS infectious diseases · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. The expanding world of DNA and RNA.Current opinion in chemical biology · 2016
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iain S MacPhersonDepartment of Chemistry, Brandeis University, 415 South St., Waltham, MA 02454, USA.
J Sebastian Temme
Sevan Habeshian
Krzysztof Felczak
Krzysztof Pankiewicz
Lizbeth Hedstrom
Isaac J Krauss

Funding

INOSINE MONOPHOSPHATE DEHYDROGENASER01GM054403 · NIGMS · BRANDEIS UNIVERSITY · PI HEDSTROM, LIZBETH K. · 1998 to 2016
$4.2M
Rational and Combinatorial Design of Immunogens to Elicit 2G12-like AntibodiesR01AI090745 · NIAID · BRANDEIS UNIVERSITY · PI KRAUSS, ISAAC JONATHAN · 2010 to 2022
$3.9M
Development of IMPDH-Targeted Drugs against CrytosporidiumU01AI075466 · NIAID · BRANDEIS UNIVERSITY · PI HEDSTROM, LIZBETH K. · 2007 to 2010
$3.3M
NIAID NIH HHS R01 AI090745NIAID NIH HHS U01 AI075466NIAID NIH HHS U01 AI75466-01NIGMS NIH HHS R01 GM054403
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DesignGlycoconjugatesAntibodies, MonoclonalAzidesBase SequenceBinding SitesBroadly Neutralizing AntibodiesDirected Molecular EvolutionDNAGene LibraryGlycosylationHIV AntibodiesHIV Envelope Protein gp120LigandsMannosidesMolecular Sequence Data2G12 monoclonal antibodyAntibodies, MonoclonalAzidesBroadly Neutralizing AntibodiesDNAGlycoconjugatesHIV AntibodiesHIV Envelope Protein gp120LigandsMannosides

Identifiers

PMID22191092
PMCPMC3900255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.