ArticleParkinson's disease2012
Impact of anxiety on quality of life in Parkinson's disease.
Article in Parkinson's disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 89 citations in OpenAlex.
- Cognitive-Behavioral Therapy for Anxiety in Parkinson's Disease.Behavior modification · 2020Trial
- Sensory focused exercise improves anxiety in Parkinson's disease: A randomized controlled trial.PloS one · 2020Trial
- The cognition and emotional well-being indices of the Parkinson's disease questionnaire-39: what do they really measure?Parkinsonism & related disorders · 2014Trial
- Does anxiety cause freezing of gait in Parkinson's disease?PloS one · 2014Trial
- Do we need drugs for psychiatric symptoms specifically for Parkinson's disease?Journal of Parkinson's disease · 2026Review
- Probiotic supplementation for anxiety symptoms in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial.NPJ Parkinson's disease · 2026Article
- Article
- Adjunctive EGb 761 treatment in patients with Parkinson's disease: a case series.Frontiers in aging neuroscience · 2026Article
- Multidimensional factors of health-related quality of life in parkinson's disease using ensemble learning and network analysis.Scientific reports · 2025Article
- Article
- Using Principles of Cognitive Behavioral Therapy to Treat Anxiety in Parkinson's Disease.Movement disorders clinical practice · 2025Review
- Validation of the English version of the Parkinson Anxiety Scale in two Canadian Parkinson's disease samples.Clinical parkinsonism & related disorders · 2025Article
- Sex differences in behavioral measures of anxiety in a recessive gene knockout (Frontiers in behavioral neuroscience · 2025Article
- An examination of anxiety and its influence on health-related quality of life in Parkinson's disease using the geriatric anxiety scale: a cross-sectional study.BMC geriatrics · 2024Article
- Electrophysiological signatures of anxiety in Parkinson's disease.Translational psychiatry · 2024Article
- Association of caregiver strain with the trajectory of quality of life in Parkinson's disease.Parkinsonism & related disorders · 2023Article
- Predictors of health-related quality of life in Parkinson's disease: the impact of overlap between health-related quality of life and clinical measures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Effectiveness and safety of herbal medicine Ukgansan for clinical symptoms in Parkinson's disease: A pilot, randomized, assessor-blinded clinical trial.Frontiers in neurology · 2022Article
- Patient and caregiver outcomes with levodopa-carbidopa intestinal gel in advanced Parkinson's disease.NPJ Parkinson's disease · 2021Article
- Perceived Health, Psychological Distress, and Subjective Well-Being among Older Adults with Parkinson's Disease: A Cross-Lagged Analysis.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In Parkinson's disease (PD), both the patient and the health care provider look for ways to preserve the patient's quality of life. Many studies focus on the impact of depression and motor disability on poor life quality but neglect to examine the role of anxiety. We investigated the impact of anxiety and depression on health-related quality of life in PD, using the Parkinson's Disease Quality of Life measure (PDQ-39). Symptoms of anxiety, more than depression, cognitive status, or motor stage, significantly affected quality of life in 38 nondemented patients with mild-to-moderate motor disability. Stepwise regression analyses revealed that anxiety explained 29% of the variance in the PDQ-39 sum score, and depression explained 10% of the variance beyond that accounted for by anxiety. The findings suggest that primary management of anxiety as well as depression may be important to optimizing the quality of life of PD patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.