SynthesisDeutsches Arzteblatt international2011
The effect of overweight and nutrition on prognosis in breast cancer.
Synthesis in Deutsches Arzteblatt international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Pooled it
- Weight Loss and Mortality in Overweight and Obese Cancer Survivors: A Systematic Review.PloS one · 2017Pooled it
- Dietary fat in breast cancer survival.Annual review of nutrition · 2013Pooled it
- Breast Cancer and Cardiovascular Risk: The Role of Dyslipidemia, Inflammation and Obesity.Diagnostics (Basel, Switzerland) · 2026Review
- App-Based Lifestyle Intervention (PINK! Coach) in Breast Cancer Patients-A Real-World-Data Analysis.Cancers · 2024Article
- Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging.Archives of toxicology · 2023Review
- Association between high body mass index and prognosis of patients with early-stage breast cancer: A systematic review and meta-analysis.Cancer pathogenesis and therapy · 2023Review
- Current research trends, hotspots, and frontiers of medical nutrition therapy on cancer: a bibliometric analysis.Frontiers in oncology · 2023Article
- Dietary Fat Intake: Associations with Dietary Patterns and Postmenopausal Breast Cancer-A Case-Control Study.Cancers · 2022Article
- Review
- Article
- Rationale and description of a lifestyle intervention programme to achieve moderate weight loss in women with non-metastatic breast cancer: the lifestyle intervention part of the SUCCESS C Study.BMJ nutrition, prevention & health · 2020Article
- Magnetic resonance angiography reveals increased arterial blood supply and tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer.NMR in biomedicine · 2020Article
- Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer.Geburtshilfe und Frauenheilkunde · 2018Article
- Can Nutrition Lower the Risk of Recurrence in Breast Cancer?Breast care (Basel, Switzerland) · 2018Review
- Routine treatment and outcome of breast cancer in younger versus elderly patients: results from the SENORA project of the prospective German TMK cohort study.Breast cancer research and treatment · 2018Article
- MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer.NMR in biomedicine · 2017Article
- [The way from cost approval to bariatric surgery : Analysis of resource utilization in a maximum care hospital].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017Article
- Consumption of vegetables and fruits and breast cancer survival: a systematic review and meta-analysis.Scientific reports · 2017Article
- Impact of Social and Built Environment Factors on Body Size among Breast Cancer Survivors: The Pathways Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast cancer is the most common cancer in women. Body weight and nutrition are known to play an important role in its pathogenesis. The question thus arises whether lifestyle factors might influence the prognosis of breast cancer, potentially offering new approaches for secondary prevention.
methodsWe selectively searched the Medline database for all studies and meta-analyses on this topic that were published from 1966 to June 2010. We evaluated the cohort studies, interventional trials, and meta-analyses with respect to three target variables: tumor recurrence, tumor-specific mortality, and overall mortality.
resultsA high body-mass index (BMI) at the time of diagnosis of breast cancer is associated with higher overall mortality, as is weight gain at later times. A low-fat diet rich in fruit, vegetables, and fiber seems to be weakly associated with a better prognosis. On other hand, there is no evidence for any benefit from micronutrients, supplements, or antioxidant foods. Alcohol consumption does not affect the outcome in breast cancer. Two intervention trials of reduced fat intake showed no effect on survival, but the target of the intervention was not met in either trial.
conclusionThe intervention trials yielded negative results. Nevertheless, in view of the methodological difficulties in this area of research and the overall life situation of women with breast cancer, the authors recommend a health-promoting lifestyle with avoidance of overweight and a low-fat diet rich in fruit, vegetables, and fiber.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.