ArticleJournal of biomedicine & biotechnology2011
Diffusion tensor MRI to assess damage in healthy and dystrophic skeletal muscle after lengthening contractions.
Article in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using MRI to quantify skeletal muscle pathology in Duchenne muscular dystrophy: A systematic mapping review.Muscle & nerve · 2021Pooled it
- The Relationship Between Magnetic Resonance Diffusion Tensor Imaging Parameters and Muscle Dysfunction in Patients with Osteoporosis: A Cross-Sectional Retrospective Study.International journal of general medicine · 2026Article
- Visualization and quantification of facial muscles with 9.4T MRI-DTI in common marmosets (Royal Society open science · 2025Article
- CORP: In vivo muscle strength-perspectives on the design and interpretation of preclinical animal studies.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Review
- Significant age-related differences between lower leg muscles of older and younger female subjects detected by ultrashort echo time magnetization transfer modeling.NMR in biomedicine · 2024Article
- The impact of diffusion tensor imaging tractography settings on muscle fascicle architecture and diffusion parameter estimates: Tract length, completion, and curvature are most sensitive to tractography settings.NMR in biomedicine · 2024Article
- Diffusion tensor imaging reveals subclinical alterations in muscles of patients with Becker muscular dystrophy.The British journal of radiology · 2024Article
- Changes in lumbar muscle diffusion tensor indices with age.BJR open · 2024Article
- Cardiac computer tomography-derived radiomics in assessing myocardial characteristics at the connection between the left atrial appendage and the left atrium in atrial fibrillation patients.Frontiers in cardiovascular medicine · 2024Article
- Robust Assessment of Macromolecular Fraction (MMF) in Muscle with Differing Fat Fraction Using Ultrashort Echo Time (UTE) Magnetization Transfer Modeling with Measured T1.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Diffusion tensor imaging indices of acute muscle damage are augmented after exercise in peripheral arterial disease.European journal of applied physiology · 2021Article
- Exercise-induced muscle damage: multi-parametric MRI quantitative assessment.BMC musculoskeletal disorders · 2021Article
- Muscle phenotype of a rat model of Duchenne muscular dystrophy.Muscle & nerve · 2020Article
- Paraspinal Muscle DTI Metrics Predict Muscle Strength.Journal of magnetic resonance imaging : JMRI · 2019Article
- Normalized STEAM-based diffusion tensor imaging provides a robust assessment of muscle tears in football players: preliminary results of a new approach to evaluate muscle injuries.European radiology · 2018Article
- Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis.Frontiers in physiology · 2018Article
- Non-invasive assessment of muscle injury in healthy and dystrophic animals with electrical impedance myography.Muscle & nerve · 2017Article
- Impaired contractile function of the supraspinatus in the acute period following a rotator cuff tear.BMC musculoskeletal disorders · 2017Article
- Magnetic Resonance Monitoring of Disease Progression in mdx Mice on Different Genetic Backgrounds.The American journal of pathology · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The purpose of this study was to determine if variables calculated from diffusion tensor imaging (DTI) would serve as a reliable marker of damage after a muscle strain injury in dystrophic (mdx) and wild type (WT) mice. Unilateral injury to the tibialis anterior muscle (TA) was induced in vivo by 10 maximal lengthening contractions. High resolution T1- and T2-weighted structural MRI, including T2 mapping and spin echo DTI was acquired on a 7T small animal MRI system. Injury was confirmed by a significant loss of isometric torque (85% in mdx versus 42% in WT). Greater increases in apparent diffusion coefficient (ADC), axial, and radial diffusivity (AD and RD) of the injured muscle were present in the mdx mice versus controls. These changes were paralleled by decreases in fractional anisotropy (FA). Additionally, T2 was increased in the mdx mice, but the spatial extent of the changes was less than those in the DTI parameters. The data suggest that DTI is an accurate indicator of muscle injury, even at early time points where the MR signal changes are dominated by local edema.
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