Evidence map›Paper›PMID 22190650›Full record

ArticleRadiology2012

Science to practice: Can contrast-enhanced US of targeted microbubbles be used to monitor and quantify inflammation in patients with inflammatory bowel disease?

Flemming Forsberg

Abstract readComment
PubMed Publisher
In one paragraph

Article in Radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Flemming ForsbergDepartment of Radiology, Thomas Jefferson University Hospital, 132 S 10th St, PA 19107, USA. flemming.forsberg@jefferson.edu
Thomas Jefferson University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deshpande et al (1) have shown that P-selectin-targeted microbubbles (MBs) can be used to monitor the expression of this molecule as a marker of inflammation in a murine model of inflammatory bowel disease (IBD). If these results can be reproduced in future clinical trials, contrast material–enhanced ultrasound (US) of targeted MBs (US molecular imaging) will enable accurate monitoring of inflammation and, specifically, response to IBD therapy, which should improve clinical outcomes.

Indexed as

AnimalsInflammatory Bowel DiseasesP-SelectinUltrasonographyP-Selectin

Identifiers

PMID22190650
OpenAlexW2170843358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.